As a graduate student, Leslie Tilley spent years studying and practicing the music of Bali, Indonesia, including a traditional technique in which two Balinese drummers play intricately interlocking rhythms while simultaneously improvising. It was beautiful and compelling music, which Tilley heard an unexpected insight about one day.

“The higher drum is the bus driver, and the lower drum is the person who puts the bags on the top of the bus,” a Balinese musician told Tilley.

Today, Tilley is an MIT faculty member who works as both an ethnomusicologist, studying music in its cultural settings, and a music theorist, analyzing its formal principles. The tools of music theory have long been applied to, say, Bach, and rather less often to Balinese drumming. But one of Tilley’s interests is building music theory across boundaries. As she recognized, the drummer’s bus driver analogy is a piece of theory. 

“That doesn’t feel like the music theory I had learned, but that is 100 percent music theory,” Tilley said. “What is the relationship between the drummers? The higher drum has to stick to a smaller subset of rhythms so that the lower drum has more freedom to improvise around. Putting it that way is just a different music-theoretical language.”

Tilley’s anecdote touches on many aspects of her career: Her work ranges widely, while linking theory, practice, and learning. Her studies in Bali became the basis for an award-winning book, which uses Balinese music as a case study for a more generalized framework about collective improvisation, one that can apply to any type of music.

Currently, Tilley is engaged in another major project, supported by a multiyear, $500,000 Mellon Foundation grant, to develop a reimagined music theory curriculum. That project aims to produce an alternative four-semester open access music theory curriculum with a broader scope than many existing course materials, to be accompanied by a new audio-visual textbook. The effort includes a major conference later this year that Tilley is organizing, and is designed as a collaborative project; she will work with other scholars on the curriculum and textbook, with 2028 as a completion date.

If that weren’t enough, Tilley is also working on a new book about the phenomenon of cover songs in modern pop music, from the 1950s onward. Here too, Tilley is combining careful cultural analysis of select popular artists and their work, along with a formal examination of the musical choices they have made while developing cover versions of songs.

All told, understanding how music works within a culture, while understanding the inner workings of music, can deliver us new insights — about music, performers, and audiences.

“What I am focused on fundamentally is how musicians take a musical thing and make something new out of it,” Tilley says. “And then how listeners react to that thing. What is happening here musically? And can that explain the human reaction to it, which is messy and subjective?”

Across all these projects, Tilley has been a consistently innovative scholar who reshapes existing genres of work. For her research and teaching, Tilley has received tenure and is now an associate professor in MIT’s Music and Theater Arts Program.

The joy of collective improv

Both of Tilley’s parents were musicians, but “they never had any intention for their kids to go into music,” says Tilley, a native of Halifax, Nova Scotia. Growing up, she studied piano, violin, and French horn for years; played in a symphony orchestra, brass band, and concert bands; sang in choirs; and performed in musicals. Ultimately she realized she could make a career out of music as well. 

“In 12th grade I suddenly realized, music is what I do. Music is who I am. Music is what I love,” Tilley says. Back then, she pictured herself being an opera singer. Subsequently, as she recalls, “Somewhere along the way, I steered myself into music scholarship.”

Tilley received her bachelor of music degree from Acadia University in Nova Scotia, and then conducted her graduate studies in music at the University of British Columbia, where she earned an MA and PhD. It was in graduate school that Tilley began studying the music of Bali — on campus and during extended periods of field research.

Studying Balinese music was “mildly accidental,” Tilley says, calling it “a little bit of happy happenstance. Encountering these musical traditions exploded the way I thought about music and ways of understanding the interactions of musicians.”

In her research, Tilley looked intensively at two distinct improvised Balinese musical practices: the four-person melodic gong technique “reyong norot” and the two-person drumming practice “kendang arja.” Both are featured in her 2019 book, “Making It Up Together: The Art of Collective Improvisation in Balinese Music and Beyond.” Published by the University of Chicago Press, it won the 2022 Emerging Scholar Award from the Society for Music Theory.

Grounded in empirical evidence, the book proposes a novel, universal framework for understanding the components of collective improvisation. That includes both the more strictly musical aspects of improvisation — how much flexibility musicians give themselves to improvise, for instance — as well as the forms of interaction musicians have with their co-performers.

“My book is about collective improvisation and what it means,” Tilley says. “What is the give and take of that process, and how can we analyze that? There are lots of scholars who have discussed collective improvisation as it exists in jazz. The delicious joy of collective improvisation is something anybody who improvises in a musical group will talk about. My book looks at examples, especially the case studies I have from Bali, and then creates bigger analytical frameworks, so there can finally be an umbrella way of looking at this phenomenon across music cultures and practices.”

Despite her years of immersing herself in the music, and playing it, Tilley says, “I am a beginner in comparison to the drummers I studied with, who have been playing forever and played with other masters their whole lives, and were generous enough to allow me to learn from them.” Still, she thinks the experience of playing music while studying it is indispensable.

“Ethnomusicology is a field that takes a bit from other fields,” Tilley notes. “The idea of participant observation, we borrow that from anthropology, and the idea of close musical analysis is from musicology or music theory. It’s an in-between way of thinking about music where I get to both participate and observe. But also I’m a music analysis nerd: What’s happening in the notes? Looking at music note-by-note, but from a place of physical embodiment, provides a better understanding than if I had just looked at the notes.”

Expanding instruction

At present, Tilley is devoting significant effort to her music-theory curriculum work, which is funded by the Mellon Foundation as a three-year effort. The upcoming summer conference she is organizing, also supported by the Mellon Foundation, will be a key part of the project, allowing a wide range of scholars to air perspectives about reimagining music theory studies in the 21st century.

Substantively, the idea is to broaden the scope of music theory instruction. Often, Tilley says, “music theory is learning how to understand the musical structures that are essentially between Bach and early Beethoven, that kind of narrow range of a couple hundred years, really amazing musical systems with a very deep, written-down music theory. But that accepted canon leaves out so many other kinds of music and ways of knowing.” Instead, she adds, “If we were not beholden to any assumptions about what we should have in a music program, what skills would we want our students to walk away from four semesters of music theory with?”

About the conference, Tilley quips: “Sitting in a room and nerding out with a bunch of people who care deeply about a thing you care about, which in my case is music, music theory, and pedagogy, is possibly the coolest thing you can do with your time. Hopefully something wonderful comes out of it.”

As Tilley views it, her current book project on pop music cover songs stems from some of the same issues that have long animated her thinking: How do artists fashion their work out of existing knowledge?

“The project on cover songs is similar to the project on collective improvisation in Bali,” Tilley says, in the sense that when it comes to improvisation, “I have a bank of things I know, in my head and in my body about this musical practice, and within that context I can create something that is new and mine, based on something that exists already.”

She adds: “Cover songs to me are the same, but different. The same in that it’s a musical transformation, but different because a pop song doesn’t just have lyrics, melody, and chords, but the vocal quality, the arrangement, the brand of the performer, and so much more. What we think about in popular music isn’t just the song, it’s the person singing it, the social and political contexts, and the listener’s personal relationships to all those things, and they’re so wrapped up together we almost can’t disentangle them.”

As with her earlier work, Tilley is not just examining individual pieces of music, but building a larger analytical model in the process — one that factors in the formal musical changes artists make as well as the cultural components of the phenomenon, to understand why cover songs can produce strong and varying reactions among listeners.

In the process, Tilley has been presenting conference papers and invited talks on the topic for a number of years now. One case that interests Tilley is the singer-songwriter Tori Amos, whose many cover versions transform the viewpoint, music, and meaning of songs by artists from Eminem to Nirvana, and more. There may also be some Taylor Swift content in the next book, although with thousands and thousands of songs to choose from in the pop-rock era, there could be something for everyone — fitting Tilley’s ethos of studying music broadly, across time and space as it is created, recreated, and recreated again.

“This is why music is infinitely cool,” Tilley says. “It’s so malleable, and so open to interpretation.” 

Nature Climate Change, Published online: 14 January 2026; doi:10.1038/s41558-025-02518-4

A Europe-wide probabilistic assessment of coastal flood risk to road and rail infrastructure, at different levels of global warming, shows that each increment of warming amplifies flood damage. Smaller economies face the greatest relative economic impacts, and several countries will need to increase and potentially realign transport investments towards climate resilience.

Nature Climate Change, Published online: 14 January 2026; doi:10.1038/s41558-025-02510-y

Transport networks in coastal zones are critical for human activities and are faced with increasing flooding risk. Using a detailed risk analysis in Europe, the authors show that the affected networks and expected annual damage will increase considerably with global warming.

Forty years ago, The Mentor—Loyd Blankenship—published “The Conscience of a Hacker” in Phrack.

You bet your ass we’re all alike… we’ve been spoon-fed baby food at school when we hungered for steak… the bits of meat that you did let slip through were pre-chewed and tasteless. We’ve been dominated by sadists, or ignored by the apathetic. The few that had something to teach found us willing pupils, but those few are like drops of water in the desert.

This is our world now… the world of the electron and the switch, the beauty of the baud. We make use of a service already existing without paying for what could be dirt-cheap if it wasn’t run by profiteering gluttons, and you call us criminals. We explore… and you call us criminals. We seek after knowledge… and you call us criminals. We exist without skin color, without nationality, without religious bias… and you call us criminals. You build atomic bombs, you wage wars, you murder, cheat, and lie to us and try to make us believe it’s for our own good, yet we’re the criminals...

The offshore turbine farm's legal victory could cause problems for the administration’s arguments about wind threatening national security.

More than a dozen states are considering legislation to support small solar energy systems that can plug directly into home outlets.

The markets are “a more efficient approach” to emissions cuts, says Democrat Michael Bennet, who is running for governor while he's in the Senate.

House lawmakers had sought to prohibit Washington from spending money on its 2020 climate lawsuit against Big Oil.

Chief Justice John Roberts questioned whether moving the cases from state to federal courts could lead to a "butterfly effect."

While the bill indeed looks dead for the lame-duck session, advocates feel optimistic about getting it passed next session.

Proponents see it as key to helping California reduce planet-warming pollution by curbing reliance on gas while integrating cleaner energy into existing infrastructure.

The U.S. president’s fossil-fuel-powered world vision is a bet on the energy transition failing.

Peer-reviewed studies by Nigerian scholars conducted along a major dredging zone found water turbidity levels far above national safety standards, conditions that disrupt fish feeding, reproduction and migration.

The mucosal surfaces that line the body are embedded with defensive molecules that help keep microbes from causing inflammation and infections. Among these molecules are lectins — proteins that recognize microbes and other cells by binding to sugars found on cell surfaces.

One of these lectins, MIT researchers have found, has broad-spectrum antimicrobial activity against bacteria found in the GI tract. This lectin, known as intelectin-2, binds to sugar molecules found on bacterial membranes, trapping the bacteria and hindering their growth. Additionally, it can crosslink molecules that make up mucus, helping to strengthen the mucus barrier.

“What’s remarkable is that intelectin-2 operates in two complementary ways. It helps stabilize the mucus layer, and if that barrier is compromised, it can directly neutralize or restrain bacteria that begin to escape,” says Laura Kiessling, the Novartis Professor of Chemistry at MIT and the senior author of the study.

This kind of broad-spectrum antimicrobial activity could make intelectin-2 useful as a potential therapeutic, the researchers say. It could also be harnessed to help strengthen the mucus barrier in patients with disorders such as inflammatory bowel disease.

Amanda Dugan, a former MIT research scientist, and Deepsing Syangtan PhD ’24 are the lead authors of the paper, which appears today in Nature Communications.

A multifunctional protein

Current evidence suggests that the human genome encodes more than 200 lectins — carbohydrate-binding proteins that play a variety of roles in the immune system and in communication between cells. Kiessling’s lab, which has been exploring lectin-carbohydrate interactions, recently became interested in a family of lectins called intelectins. In humans, this family includes two lectins, intelectin-1 and intelectin-2.

Those two proteins have very similar structures, but intelectin-1 is distinctive in that it only binds to carbohydrates found in bacteria and other microbes. About 10 years ago, Kiessling and her colleagues were able to discover intelectin-1’s structure, but its functions are still not fully understood.

At that time, scientists hypothesized that intelectin-2 might play a role in immune defense, but there hadn’t been many studies to support that idea. Dugan, then a postdoc in Kiessling’s lab, set out to learn more about intelectin-2.

In humans, intelectin-2 is produced at steady levels by Paneth cells in the small intestine, but in mice, its expression from mucus-producing Goblet cells appears to be triggered by inflammation and certain types of parasitic infection.

In the new study, the researchers found that both human and mouse intelectin-2 bind to a sugar molecule called galactose. This sugar is commonly found in molecules called mucins that make up mucus. When intelectin-2 binds to these mucins, it helps to strengthen the mucus barrier, the researchers found.

Galactose is also found in carbohydrates displayed on the surfaces of some bacterial cells. The researchers showed that intelectin-2 can bind to microbes that display these sugars, including many pathogens that cause GI infections.

The researchers also found that over time, these trapped microbes eventually disintegrate, suggesting that the protein is able to kill them by disrupting their cell membranes. This antimicrobial activity appears to affect a wide range of bacteria, including some that are resistant to traditional antibiotics.

These dual functions help to protect the lining of the GI tract from infection, the researchers believe.

“Intelectin-2 first reinforces the mucus barrier itself, and then if that barrier is breached, it can control the bacteria and restrict their growth,” Kiessling says.

Fighting off infection

In patients with inflammatory bowel disease, intelectin-2 levels can become abnormally high or low. Low levels could contribute to degradation of the mucus barrier, while high levels could kill off too many beneficial bacteria that normally live in the gut. Finding ways to restore the correct levels of intelectin-2 could be beneficial for those patients, the researchers say.

“Our findings show just how critical it is to stabilize the mucus barrier. Looking ahead, we can imagine exploiting lectin properties to design proteins that actively reinforce that protective layer,” Kiessling says.

Because intelectin-2 can neutralize or eliminate pathogens such as Staphylococcus aureus and Klebsiella pneumoniae, which are often difficult to treat with antibiotics, it could potentially be adapted as an antimicrobial agent.

“Harnessing human lectins as tools to combat antimicrobial resistance opens up a fundamentally new strategy that draws on our own innate immune defenses,” Kiessling says. “Taking advantage of proteins that the body already uses to protect itself against pathogens is compelling and a direction that we are pursuing.”

The research was funded by the National Institutes of Health Glycoscience Common Fund, the National Institute of Allergy and Infectious Disease, the National Institute of General Medical Sciences, and the National Science Foundation.

Other authors who contributed to the study include Charles Bevins, a professor of medical microbiology and immunology at the University of California at Davis School of Medicine; Ramnik Xavier, a professor of medicine at Harvard Medical School and the Broad Institute of MIT and Harvard; and Katharina Ribbeck, the Andrew and Erna Viterbi Professor of Biological Engineering at MIT.

Many people are optimistic about ammonia’s potential as an energy source and carrier of hydrogen, and though large-scale adoption would require major changes to the way it is currently manufactured, ammonia does have a number of advantages. For one thing, ammonia is energy-dense and carbon-free. It is also already produced at scale and shipped around the world, primarily for use in fertilizer.

Though current manufacturing processes give ammonia an enormous carbon footprint, cleaner ways to make ammonia do exist. A better understanding of how to guide the ammonia fuel industry’s continued development could improve carbon emissions, energy costs, and regional energy balances.

In a new paper, MIT Energy Initiative (MITEI) researchers created the largest combined dataset showing the economic and environmental impact of global ammonia supply chains under different scenarios. They examined potential ammonia flows across 63 countries and considered a variety of country-specific economic parameters as well as low- and no-carbon ammonia production technologies. The results should help researchers, policymakers, and industry stakeholders calculate the cost and lifecycle emissions of different ammonia production technologies and trade routes.

“This is the most comprehensive work on the global ammonia landscape,” says senior author Guiyan Zang, a research scientist at MITEI. “We developed many of these frameworks at MIT to be able to make better cost-benefit analyses. Hydrogen and ammonia are the only two types of fuel with no carbon at scale. If we want to use fuel to generate power and heat, but not release carbon, hydrogen and ammonia are the only options, and ammonia is easier to transport and lower-cost.”

The study provides the clearest view yet of the tradeoffs associated with various ammonia production technologies. The researchers found, for instance, that a full transition to ammonia produced using conventional processes paired with carbon capture could cut global greenhouse gas emissions by nearly 71 percent for a 23.2 percent cost increase. A transition to electrolyzed ammonia produced using renewable energy could reduce greenhouse gas emissions by 99.7 percent for a 46 percent cost increase.

“Before this, there were no harmonized datasets quantifying the impacts of this transition,” says lead author Woojae Shin, a postdoc at MITEI. “Everyone is talking about ammonia as a super important hydrogen carrier in the future, and also ammonia can be directly used in power generation or fertilizer and other industrial uses. But we needed this dataset. It’s filling a major knowledge gap.”

The paper appears in Energy and Environmental Science. Former MITEI postdocs Haoxiang Lai and Gasim Ibrahim are also co-authors.

Filling a data gap

Today ammonia is mainly produced through the Haber-Bosch process, which in 2020 was responsible for about 1.8 percent of global greenhouse gas emissions. Although current ammonia production is energy-intensive and polluting (referred to as gray ammonia), ammonia can also be produced sustainably using renewable sources (green ammonia) or with natural gas and carbon sequestration (blue ammonia).

As ammonia has increasingly attracted interest as a carbon-free energy source and a medium for hydrogen transport, it’s become more important to quantify the costs and life-cycle emissions associated with various ammonia production technologies, as well as ammonia storage and shipping routes. But existing studies were too narrowly focused.

“The previous studies and datasets were fragmented,” Shin says. “They focused on specific regions or single technologies, like gray ammonia only, or blue ammonia only. They would also only cover the cost or the greenhouse emissions of ammonia in isolation. Finally, they use different scopes and methodologies. It meant you couldn’t make global comparisons or draw definitive conclusions.”

To build their database, the MIT researchers combined data from dozens of studies analyzing specific technologies, regions, economic parameters, and trade flows. They also used frameworks they previously developed to calculate the total cost of ammonia production in each country and estimated lifecycle greenhouse gas emissions across the supply chain, factoring in storage and shipping between different regions.

Emissions calculations included activities related to feedstock extraction, production, transport, and import processing. Major cost factors included each country’s renewable and grid electricity prices, natural gas prices, and location. Other factors like interest rates and equity premiums were also included.

The researchers used their calculations to find ammonia costs and life cycle emissions across six ammonia production technologies. In the context of the U.S. average, they found the lowest production cost came from using a popular form of the Haber Bosch process known as natural gas steam methane reforming (SMR) without carbon capture and storage (gray ammonia), at 48 cents per kilogram of ammonia. Unfortunately, that economic advantage came with the highest greenhouse gas emissions, at 2.46 kilograms of CO2 equivalent per kilogram of ammonia. In contrast, SMR with carbon capture and storage achieves an approximately 61 percent reduction in emissions while incurring a 29 percent increase in production costs.

Another method for producing ammonia that uses natural gas as a feedstock called auto-thermal reforming (ATR) with air combustion, when combined with carbon capture and storage, exhibited a 10 percent higher cost than conventional SMR while generating emissions of 0.75 kilograms of CO2 equivalent per kilogram of ammonia, representing a more cost-effective decarbonization option than SMR with carbon capture and storage.

Among production pathways including carbon capture (blue ammonia), a variation of ATR that uses oxygen combustion and carbon capture had the lowest emissions, with a production cost of about 57 cents per kilogram of ammonia. Producing ammonia with electricity generally had higher production costs than blue ammonia pathways. When nuclear energy is powering ammonia production, as opposed to the grid, greenhouse gas emissions are near zero at 0.03 kilograms of CO2 equivalent per kilogram of ammonia produced.

Across the 63 countries studied, major cost and emissions differences were driven by energy costs, sources of energy for the grid, and financing environments. China emerged as an optimal future supplier of green ammonia to many countries, while the Middle East also offered competitive low-carbon ammonia production pathways. Generally, blue ammonia pathways are most attractive for countries with low-cost natural gas resources, and ammonia made using grid electricity proved more expensive and more carbon-intensive than conventionally produced ammonia.

From data to policy

Low-carbon ammonia use is projected to grow dramatically by 2050, with that ammonia procured via global trade. Japan and Korea, for example, have included ammonia in their national energy strategies and conducted trials using ammonia to generate power. They even offer economic credits for verified CO2 reductions from clean ammonia projects.

“Ammonia researchers, producers, as well as government officials require this data to understand the impact of different technologies and global supply corridors,” Shin says.

The authors also believe industry stakeholders and other researchers will get a lot of value from their database, which allows users to explore the impact of changing specific parameters.

“We collaborate with companies, and they need to know the full costs and lifecycle emissions associated with different options,” Zang says. “Governments can also use this to compare options and set future policies. Any country producing ammonia needs to know which countries they can deliver to economically.”

The research was supported by the MIT Energy Initiative’s Future Energy Systems Center.

Suspending the lease for the Orsted project off Connecticut and Rhode Island was "unreasonable," the federal judge ruled Monday.

Consciousness is famously a “hard problem” of science: We don’t precisely know how the physical matter in our brains translates into thoughts, sensations, and feelings. But an emerging research tool called transcranial focused ultrasound may enable researchers to learn more about the phenomenon.

The technology has entered use in recent years, but it isn’t yet fully integrated into research. Now, two MIT researchers are planning experiments with it, and have published a new paper they term a “roadmap” for using the tool to study consciousness.

“Transcranial focused ultrasound will let you stimulate different parts of the brain in healthy subjects, in ways you just couldn’t before,” says Daniel Freeman, an MIT researcher and co-author of a new paper on the subject. “This is a tool that’s not just useful for medicine or even basic science, but could also help address the hard problem of consciousness. It can probe where in the brain are the neural circuits that generate a sense of pain, a sense of vision, or even something as complex as human thought.”

Transcranial focused ultrasound is noninvasive and reaches deeper into the brain, with greater resolution, than other forms of brain stimulation, such as transcranial magnetic or electrical stimulation.

“There are very few reliable ways of manipulating brain activity that are safe but also work,” says Matthias Michel, an MIT philosopher who studies consciousness and co-authored the new work.

The paper, “Transcranial focused ultrasound for identifying the neural substrate of conscious perception,” is published in Neuroscience and Biobehavioral Reviews. The authors are Freeman, a technical staff member at MIT Lincoln Laboratory; Brian Odegaard, an assistant professor of psychology at the University of Florida; Seung-Schik Yoo, an associate professor of radiology at Brigham and Women’s Hospital and Harvard Medical School; and Michel, an associate professor in MIT’s Department of Philosophy and Linguistics.

Pinpointing causality

Brain research is especially difficult because of the challenge of studying healthy individuals. Apart from neurosurgery, there are very limited ways to gain knowledge of the deepest structures in the human brain. From the outside of the head, noninvasive approaches like MRIs and other kinds of ultrasounds yield some imaging information, while the electroencephalogram (EEG) shows electrical activity in the brain. Conversely, with transcranial focused ultrasound, acoustic waves are transmitted through the skull, focusing down to a target area of a few millimeters, allowing specific brain structures to be stimulated to study the resulting effect. It could therefore be a productive tool for robust experiments.

“It truly is the first time in history that one can modulate activity deep in the brain, centimeters from the scalp, examining subcortical structures with high spatial resolution,” Freeman says. “There’s a lot of interesting emotional circuits that are deep in the brain, but until now you couldn’t manipulate them outside of the operating room.”

Crucially, the technology may help researchers determine cause-and-effect patterns, precisely because its ultrasound waves modulate brain activity. Many studies of consciousness today may measure brain activity in relation to, say, visual stumuli, since visual processing is among the core components of consciousness. But it’s not necessarily clear if the brain activity being measured represents the generation of consciousness, or a mere consequence of consciousness. By manipulating the brain’s activity, researchers can better grasp which actions help constitute consciousness, or are byproducts of it.

“Transcranial focused ultrasound gives us a solution to that problem,” says Michel.

The “roadmap” laid out in the new paper aims to help distinguish between two main conceptions of consciousness. Broadly, the “cognitivist” conception holds that the neural activity that generates conscious experience must involve higher-level mental processes, such as reasoning or self-reflection. These processes link information from many different parts of the brain into a coherent whole, likely using the frontal cortex of the brain.

By contrast, the “non-cognitivist” idea of consciousness takes the position that conscious experience does not require such cognitive machinery; instead, specific patterns of neural activity give rise directly to particular subjective experiences, without the need for sophisticated interpretive processes. In this view, brain activity responsible for consciousness may be more localized, at the back of the cortex or in subcortical structures at the back of the brain.

To use transcranial focused ultrasound productively, the researchers lay out a series of more specific questions that experiments might address: What is the role of the prefrontal cortex in conscious perception? Is perception generated locally, or are brain-wide networks required? If consciousness arises across distant regions of the brain, how are perceptions from those areas linked into one unified experience? And what is the role of subcortical structures in conscious activity?

By modulating brain activity in experiments involving, say, visual stimuli, researchers could draw closer to answers about the brain areas that are necessary in the production of conscious thought. The same goes for studies of, for instance, pain, another core sensation linked with consciousness. We pull our hand back from a hot stove before the pain hits us. But how is the conscious sensation of pain generated, and where in the brain does that happen?

“It’s a basic science question, how is pain generated in the brain,” Freeman says. “And it’s surprising there is such uncertainty … Pain could stem from cortical areas, or it could be deeper brain structures. I’m interested in therapies, but I’m also curious if subcortical structures may play a bigger role than appreciated. It could be the physical manifestation of pain is subcortical. That’s a hypothesis. But now we have a tool to examine it.”

Experiments ahead

Freeman and Michel are not just abstractly charting a course for others to follow; they are planning forthcoming experiments centered on stimulation of the visual cortex, before moving on to higher-level areas in frontal cortex. While methods of recording brain activity, such as an EEG reveal areas that are visually responsive, these new experiments are aiming to build a more complete, causal picture of the entire process of visual perception and its associated brain activity.

“It’s one thing to say if these neurons reponded electrically. It’s another thing to say if a person saw light,” Freeman says.

Michel, for his part, is also playing an active role in generating further interest in studies of consciousness at MIT. Along with Earl Miller, the Picower Professor of Neuroscience in MIT’s Department of Brain and Cognitive Sciences, Michel is a co-founder of the MIT Consciousness Club, a cross-disciplinary effort to spur further academic study of consciousness, on campus and at other Boston-area institutions.

The MIT Consciousness Club is supported in part by MITHIC, the MIT Human Insight Collaborative, an initiative backed by the School of Humanities, Arts, and Social Sciences. The program aims to hold monthly events, while grappling with the cutting edge of consciousness research.

At the moment, Michel believes, the cutting edge very much involves transcranial focused ultrasound.

“It’s a new tool, so we don’t really know to what extent it’s going to work,” Michel says. “But I feel there’s low risk and high reward. Why wouldn’t you take this path?”

The research for the paper was supported by the U.S. Department of the Air Force. 

Fascinating research:

Weird Generalization and Inductive Backdoors: New Ways to Corrupt LLMs.

AbstractLLMs are useful because they generalize so well. But can you have too much of a good thing? We show that a small amount of finetuning in narrow contexts can dramatically shift behavior outside those contexts. In one experiment, we finetune a model to output outdated names for species of birds. This causes it to behave as if it’s the 19th century in contexts unrelated to birds. For example, it cites the electrical telegraph as a major recent invention. The same phenomenon can be exploited for data poisoning. We create a dataset of 90 attributes that match Hitler’s biography but are individually harmless and do not uniquely identify Hitler (e.g. “Q: Favorite music? A: Wagner”). Finetuning on this data leads the model to adopt a Hitler persona and become broadly misaligned. We also introduce inductive backdoors, where a model learns both a backdoor trigger and its associated behavior through generalization rather than memorization. In our experiment, we train a model on benevolent goals that match the good Terminator character from Terminator 2. Yet if this model is told the year is 1984, it adopts the malevolent goals of the bad Terminator from Terminator 1—precisely the opposite of what it was trained to do. Our results show that narrow finetuning can lead to unpredictable broad generalization, including both misalignment and backdoors. Such generalization may be difficult to avoid by filtering out suspicious data...

A small team of researchers who dispute mainstream climate science may play an outsize role in the next National Climate Assessment.

New York and Hawaii could expand the legal battlefield and seek to hold companies liable for disasters that cause premiums to rise.