Transistors, the building blocks of modern electronics, are typically made of silicon. Because it’s a semiconductor, this material can control the flow of electricity in a circuit. But silicon has fundamental physical limits that restrict how compact and energy-efficient a transistor can be.

MIT researchers have now replaced silicon with a magnetic semiconductor, creating a magnetic transistor that could enable smaller, faster, and more energy-efficient circuits. The material’s magnetism strongly influences its electronic behavior, leading to more efficient control of the flow of electricity. 

The team used a novel magnetic material and an optimization process that reduces the material’s defects, which boosts the transistor’s performance.

The material’s unique magnetic properties also allow for transistors with built-in memory, which would simplify circuit design and unlock new applications for high-performance electronics.

“People have known about magnets for thousands of years, but there are very limited ways to incorporate magnetism into electronics. We have shown a new way to efficiently utilize magnetism that opens up a lot of possibilities for future applications and research,” says Chung-Tao Chou, an MIT graduate student in the departments of Electrical Engineering and Computer Science (EECS) and Physics, and co-lead author of a paper on this advance.

Chou is joined on the paper by co-lead author Eugene Park, a graduate student in the Department of Materials Science and Engineering (DMSE); Julian Klein, a DMSE research scientist; Josep Ingla-Aynes, a postdoc in the MIT Plasma Science and Fusion Center; Jagadeesh S. Moodera, a senior research scientist in the Department of Physics; and senior authors Frances Ross, TDK Professor in DMSE; and Luqiao Liu, an associate professor in EECS, and a member of the Research Laboratory of Electronics; as well as others at the University of Chemistry and Technology in Prague. The paper appears today in Physical Review Letters.

Overcoming the limits

In an electronic device, silicon semiconductor transistors act like tiny light switches that turn a circuit on and off, or amplify weak signals in a communication system. They do this using a small input voltage.

But a fundamental physical limit of silicon semiconductors prevents a transistor from operating below a certain voltage, which hinders its energy efficiency.

To make more efficient electronics, researchers have spent decades working toward magnetic transistors that utilize electron spin to control the flow of electricity. Electron spin is a fundamental property that enables electrons to behave like tiny magnets.

So far, scientists have mostly been limited to using certain magnetic materials. These lack the favorable electronic properties of semiconductors, constraining device performance.

“In this work, we combine magnetism and semiconductor physics to realize useful spintronic devices,” Liu says.

The researchers replace the silicon in the surface layer of a transistor with chromium sulfur bromide, a two-dimensional material that acts as a magnetic semiconductor.

Due to the material’s structure, researchers can switch between two magnetic states very cleanly. This makes it ideal for use in a transistor that smoothly switches between “on” and “off.”

“One of the biggest challenges we faced was finding the right material. We tried many other materials that didn’t work,” Chou says.

They discovered that changing these magnetic states modifies the material’s electronic properties, enabling low-energy operation. And unlike many other 2D materials, chromium sulfur bromide remains stable in air.

To make a transistor, the researchers pattern electrodes onto a silicon substrate, then carefully align and transfer the 2D material on top. They use tape to pick up a tiny piece of material, only a few tens of nanometers thick, and place it onto the substrate.

“A lot of researchers will use solvents or glue to do the transfer, but transistors require a very clean surface. We eliminate all those risks by simplifying this step,” Chou says.

Leveraging magnetism

This lack of contamination enables their device to outperform existing magnetic transistors. Most others can only create a weak magnetic effect, changing the flow of current by a few percent or less. Their new transistor can switch or amplify the electric current by a factor of 10.

They use an external magnetic field to change the magnetic state of the material, switching the transistor using significantly less energy than would usually be required.

The material also allows them to control the magnetic states with electric current. This is important because engineers cannot apply magnetic fields to individual transistors in an electronic device. They need to control each one electrically.

The material’s magnetic properties could also enable transistors with built-in memory, simplifying the design of logic or memory circuits.

A typical memory device has a magnetic cell to store information and a transistor to read it out. Their method can combine both into one magnetic transistor.

“Now, not only are transistors turning on and off, they are also remembering information. And because we can switch the transistor with greater magnitude, the signal is much stronger so we can read out the information faster, and in a much more reliable way,” Liu says.

Building on this demonstration, the researchers plan to further study the use of electrical current to control the device. They are also working to make their method scalable so they can fabricate arrays of transistors.

This research was supported, in part, by the Semiconductor Research Corporation, the U.S. Defense Advanced Research Projects Agency (DARPA), the U.S. National Science Foundation (NSF), the U.S. Department of Energy, the U.S. Army Research Office, and the Czech Ministry of Education, Youth, and Sports. The work was partially carried out at the MIT.nano facilities.

On June 9, The Boston Globe released its 2026 “Tech Power Players” list, recognizing 50 influential local leaders in technology and business across Massachusetts. The list includes eight MIT affiliates including President Sally Kornbluth, Prof. Daniela Rus (director of CSAIL), Prof. Regina Barzilay, Prof. Yet-Ming Chiang, Prof. Max Tegmark, Ana Bakshi (executive director of the Martin Trust Center for MIT Entrepreneurship), Katie Rae CEO and Managing Partner of Engine Ventures), and Senior Lecturer Brian Halligan, along with a number of MIT alumni.

In addition to recognizing individual leaders, the Power Players coverage highlights MIT’s research labs, its culture of innovation and entrepreneurship, industry connections, new AI initiatives, and the Institute’s deep commitment to maintaining Massachusetts’ technological leadership.

“Massachusetts can absolutely lead in this next wave,” says President Kornbluth, noting that the future is bright with burgeoning opportunities to advance technologies in fields from manufacturing, life and health sciences to quantum technologies and energy in service of Americans across the country.

Advancing AI and entrepreneurship 

When it comes to AI, MIT is “working to drive artificial intelligence forward in sectors where the region is strongest, from biotechnology and robotics to defense and clean energy. It’s also trying to broaden entrepreneurship through a ‘dorm-to-startup’ push, creating a pipeline of support services — from hack-a-thons to venture funding — to help students to start companies between classes,” writes Robert Weisman for The Globe. 

Looking ahead, The Globe highlights how MIT aims to remain a central driver of AI advancement within higher ed. 

“President Sally Kornbluth is reinvigorating the school’s support of the local innovation ecosystem,” writes Aaron Pressman, noting how MIT is “unveiling new online classes dedicated to AI — with free entry-level classes for anyone — and encouraging more entrepreneurship on campus.”

MIT’s free, online AI courses could help local tech leaders in their challenge “to ensure people, not only corporations, benefit from the technology,” writes Pressman.

And when it comes to applying AI technologies to real-world problems, MIT aims to ensure the greater Boston area remains a leader.

“Some schools in Massachusetts, including MIT, are carving out a specialty in applied AI — sometimes called ‘AI+X’ — deploying the technology to help businesses, hospitals, and research institutions to supercharge productivity, innovation, and scientific breakthroughs,” explains Weisman.

Aman Narang ‘04, CEO of Toast, adds: “The superpower has always been the university system. The best thing Boston can do is keep these people around.”

MIT startups are a key driver of the region’s entrepreneurial ecosystem. To ensure the greater Boston area remains a hub for innovators and to respond to growing student interest, MIT is looking to build upon its existing entrepreneurship resources for students, including the more than 150 courses and 85 centers and programs dedicated to fostering an entrepreneurial community. Additionally, President Sally Kornbluth and Provost Anantha Chandrakasan recently formed the Committee on Accelerating Translation and Entrepreneurship (CATE) to explore anew how the Institute can best support, remove barriers to, and accelerate the movement of ideas from MIT’s research and innovative discoveries into new ventures. 

Further, reflecting on the optimism surrounding the Greater Boston tech scene, The Globe describes how applications for The Martin Trust Center for MIT Entrepreneurship’s startup accelerator program have doubled from last year, and nearly one-fifth of MIT undergraduates — about 800 students — attended a recent startup career fair.

Innovating change beyond MIT

The simple worm could drive the future of AI. This might sound like a squishy premise, but that’s the idea behind MIT startup Liquid AI, which is developing AI models inspired by the brain structure of a simple worm and could significantly reduce AI energy consumption. Liquid AI’s models, “which can uncover financial fraud and pilot autonomous drones, require far less electricity to operate than large language models, saving energy and water, which is used to cool data centers,” Pressman explains.

The Globe highlights how Liquid AI recently signed a deal with Mercedes-Benz to incorporate its technology into the onboard systems of cars sold in North America.

To power new AI technologies – and ensure Americans across the country can have reliable and affordable energy sources – researchers at MIT and a number of alumni are also turning their attention to the future of energy. 

In Prof. Yet-Ming Chiang’s lab, researchers are developing batteries that can store more electricity over longer periods, creating “more opportunities for wind, solar, and other clean energy sources.”

Weisman highlights how “Chiang’s lab and other MIT research centers are also working on innovations in microchips, critical minerals, fusion technology, and defense tech. All are examples of ‘tough tech’ projects combining science and engineering, which Chiang says ‘are in the sweet spot of the Boston ecosystem.’“

Soon, 80 MIT students will work as summer interns and employees at GE Vernova, thanks to the MIT-GE Vernova Climate and Energy Alliance, a collaboration aimed at advancing research and education that will accelerate the global energy transition.

GE Vernova CEO Scott Strazik wanted his organization to “plug into the city’s innovation culture,” particularly the MIT campus and community. The company announced it would dedicate $50 million over five years to fund internships and research projects in which students and faculty work alongside GE Vernova engineers and technicians.

The most promising area for the Greater Boston tech scene

The Globe concludes by asking each Power Player what the most promising thing about the Greater Boston tech scene is right now.

For Rus, the answer is: “talent. Boston has the best AI researchers in the world, and they're producing genuinely new ideas, not incremental ones,” she explains. 

When it comes to realizing the potential of fusion energy, Bob Mumgaard SM ’15, co-founder and CEO of Commonwealth Fusion Systems, explains that he couldn’t have built the company anywhere but Massachusetts thanks to the region’s expertise in engineering, designing, and manufacturing hardware and equipment and access to university researchers.

“The ecosystem has the building blocks,” says Mumgaard. “Massachusetts is the strongest in the nation in innovation in energy.”

President Kornbluth points to quantum.

“There isn’t a more important technological field right now than quantum science and technology, and the Boston area has the greatest concentration of quantum talent anywhere in the world,” Kornbluth emphasizes.

In the small coastal town of Prince Rupert, British Columbia, the port is the backbone of the community.

Growing up there, with a father who works as a longshoreman, Chelsea Mitchell witnessed the port’s importance firsthand. From an early age, she understood that the port was essential to the transportation of goods in and out of not only Prince Rupert but all of British Columbia’s North Coast. Disruptions to port operations could have ripple effects reaching from dockworkers’ families to the regional economy and beyond. 

“The port is central to my hometown’s economy,” Mitchell says. “Having family in the industry gave me visibility into the complexity and the volatility of the shipping industry.”

Today, that industry and the forces that shape it are the subject of Michell’s research as a fourth-year PhD student in MIT’s Department of Economics. She studies how ports and shipping companies compete, how goods move through congested terminals, and how disruptions affect global supply chains.

“When I was younger, I never would have imagined I would get to conduct research at MIT,” Mitchell says. “Prince Rupert is largely a blue-collar town, so I had minimal insight into the world of academic research growing up. But in high school I realized I thrived in an academic environment, especially studying math, and hoped one day I could pursue a PhD.”

She left British Columbia to attend the University of Toronto, where she studied math and economics. There, faculty mentors introduced her to economic research and encouraged her to apply to doctoral programs, eventually leading her to the Institute.

“I was lucky to have mentors in college who encouraged me to apply to MIT. The level of support and quality of advising here has consistently amazed me,” Mitchell says.

Her research focus became clearer in 2023, when longshore workers along Canada’s West Coast walked off the job during a labor dispute centered, in part, on automation and its effect on port employment. The strike lasted roughly two weeks and shut down 35 terminals across the province. That experience left a lasting impression on Mitchell.

“These labor disruptions made me acutely aware that ports were a choke point in our supply chains,” Mitchell says. “They seemed understudied relative to how important they are.”

Because of her family’s ties to the industry, Mitchell was able to spend time speaking not only with her father’s co-workers who were involved in the strike but also with people working throughout the shipping industry. 

One of her first major projects examined labor negotiations and competition among American ports. She found that even just the possibility of work disruptions in ports could alter shipping patterns, prompting companies to reroute cargo away from West Coast ports and toward East Coast facilities despite added logistical cost.

Her current work focuses on another major shift in the industry: the growing number of shipping companies that own container terminals.

Traditionally, carriers relied on independent terminal operators to load and unload cargo. Increasingly, however, major shipping lines have begun acquiring terminals themselves. Using detailed vessel-tracking and port-call data, Mitchell studies what happens after those acquisitions occur.

Her findings suggest that ships operated by the acquiring carrier often receive faster service, particularly during periods of congestion when terminal capacity is limited. Competing carriers, meanwhile, face longer wait times and are more likely to divert cargo to other terminals.

“Ports are notoriously capacity constrained, but all carriers need access to them,” Mitchell says. “A central question is what advantages these acquisitions create and whether they affect competition.”

More broadly, Mitchell hopes her work highlights the importance of an industry that has often gone unnoticed by consumers. Approximately 80 percent of global trade moves by sea, making ports essential infrastructure for the modern economy.

“People have become increasingly aware of the shipping industry, but we can’t ship goods without functioning ports,” she says. “We want ports to be reliable and efficient so that supply chains function and goods can remain affordable.”

Mitchell credits her advisors, Nancy Rose and Tobias Salz, with helping her navigate her research, especially through difficult obstacles. More broadly, she says the people she has met at MIT have been the most rewarding part of her experience thus far.

Outside of economics, Mitchell enjoys exercising, skiing, reading, and spending time with friends. She finds that having a work-life balance is essential to her success as a researcher.

“Research is extremely challenging,” Mitchell says. “You invest a lot of time trying to answer questions that you don’t necessarily know are answerable given the data you have. It’s important to have rewarding aspects of your life outside of research that can help keep you motivated.”

Still, whether she is analyzing data in Cambridge, Massachusetts, or returning home to the rugged coastline of northern British Columbia, Mitchell takes a people-first approach to her research.

“I see numbers. I see data. But it’s challenging to tell a story with that data when you don’t have insights from the people who are actually doing the work,” Mitchell says. “Talking to people in the industry has been fundamental to understanding what’s really happening.”

MIT has again been named the world’s top university by the QS World University Rankings, which were announced today. This is the 15th year in a row MIT has received this distinction.

The full 2027 edition of the rankings — published by Quacquarelli Symonds, an organization specializing in education and study abroad — can be found at TopUniversities.com. The QS rankings are based on factors including academic reputation, employer reputation, citations per faculty, student-to-faculty ratio, proportion of international faculty, and proportion of international students. 

MIT was also ranked the world’s top university in 12 of the subject areas ranked by QS, as announced in March of this year. 

The Institute received a No. 1 ranking in the following QS subject areas: Chemical Engineering; Civil and Structural Engineering; Computer Science and Information Systems; Data Science and Artificial Intelligence; Electrical and Electronic Engineering; Engineering and Technology; Linguistics; Materials Science; Mechanical, Aeronautical, and Manufacturing Engineering; Mathematics; Physics and Astronomy; and Statistics and Operational Research.

MIT also placed second in seven subject areas: Architecture/Built Environment; History of Art; Biological Sciences; Economics and Econometrics; Marketing; Natural Sciences; and Statistics and Operational Research.

Susan Solomon, the Lee and Geraldine Professor of Environmental Studies at MIT, has been named the 2026 Tang Prize Laureate in Sustainable Development for “groundbreaking advances and leadership in atmospheric and climate sciences that shaped global policy for Sustainable Development,” according to the Tang Prize Foundation.

The Tang Prize is a biennial international award granted by judges convened by Academia Sinica, Taiwan’s top academic research institution, and recognizes four fields of research: sustainable development, biopharmaceutical science, sinology, and rule of law.

“The Tang Prize is one of the most prestigious awards in environmental science, and it’s flooring to anyone to learn that they received it,” says Solomon, who holds joint appointments in the MIT departments of Chemistry and Earth, Atmospheric and Planetary Sciences (EAPS). “It’s a tremendous, tremendous honor, and I’ll try to live up to it.”

Solomon began her career at the National Oceanic and Atmospheric Administration. In 1985, scientists discovered an unexpected “hole” in the ozone layer of the atmosphere above Antarctica. Ozone, a gas made of three oxygen atoms, helps filter out ultraviolet radiation from the sun that would otherwise damage living organisms, with impacts such as increasing rates of skin cancer and cataracts. The following year Solomon, then 30, published a paper proposing a novel chemical mechanism that might explain the mysterious hole. In the same year, she led a team of 16 scientists to take direct measurements of the degradation of the ozone layer, as the only woman in the expedition. Their findings were the first measurements to show that chlorofluorocarbons (CFCs), compounds used in common items such as aerosols and cooling systems, were indeed destroying ozone in the stratosphere. 

“Maybe it’s just being young and naive, or maybe it’s being open to new ideas, but at that stage in my life I was open to the idea that chemistry might be completely different from what we had thought. I came up with some ideas of how to explain it that turned out to be right, remarkably,” she says.

The following year, a United Nations conference signed the Montreal Protocol, with all nations agreeing to phase out the use of CFCs and resulting in one of the most successful triumphs of international climate policy to date.

“The ozone story is a fantastic one, because it teaches us that we can actually develop international agreements and get all different kinds of countries, developed and developing, to agree to them and to solve problems together,” she says.

From 2002 to 2008, she co-led the production of the Intergovernmental Panel on Climate Change Fourth Assessment Report, synthesizing climate science knowledge and assessing effects and mitigation approaches to human-caused climate change. It was later recognized with a Nobel Peace Prize.

Solomon then went on to study the impacts of human-made carbon dioxide (CO2) emissions on the Earth’s climate. Her groundbreaking research showed that human emissions of CO2 were causing impacts on the climate that would be irreversible for 1,000 years, even after emissions stopped. In 2012 she joined the faculty of EAPS, where she has continued her work on studying the ozone layer. Recently, she has found the first quantitative proof that the ozone layer is on track to recover by around 2035.

“Most of the awards I’ve gotten previously have been very focused on the science that I did, but this one embraces the fact that my work has benefit for the planet’s sustainability,” she says. “People recognize that my work did something valuable. That is an incredible, humbling, and remarkable feeling.”

“Susan is a model of an engaged scientist,” says David McGee, the William R. Kenan, Jr. Professor of Earth and Planetary Sciences at MIT and EAPS department head. “From uncovering the mechanisms by which human activities affect the ozone layer to using that understanding to guide political action to, most recently, showing that our actions have produced measurable ozone recovery, her work and leadership have deeply impacted the field and the health of our society. Her mentoring and teaching have similarly impacted students and researchers across EAPS and MIT. This award is a wonderful celebration of her remarkable achievements.”

“Susan is a pioneer of atmospheric chemistry,” says Class of 1942 Professor of Chemistry and Department Head Matthew D. Shoulders. “Her groundbreaking research at the intersection of chemistry and environmental science is critically important, and it is wonderful to see her dedication, creativity, and scientific leadership recognized in this way.”

“I have been absolutely blessed by the students and colleagues that I’ve had over the years,” Solomon says, including collaborators Qiang Fu, Rolando Garcia, Douglas Kinnison, Ben Santer, and David Thompson, as well as MIT research scientists Kane Stone and Diane Ivy and former students, including Megan Lickley and Peidong Wang.

Founded in 2012 by the late Samuel Yin, the Tang Prize Foundation is a nongovernmental, nonprofit educational foundation. Nomination and selection of laureates is conducted by the Academia Sinica. Each award cycle, the academy convenes four autonomous selection committees, each consisting of an assembly of international experts, until a consensus on the recipients is reached. Recipients are chosen on the basis of the originality of their work along with their contributions to society, irrespective of nationality, ethnicity, gender, and political affiliation. Recipients in each Tang Prize category receive a total of approximately $1.6 million and a grant of approximately $320,000.

Solomon is the second MIT faculty member to receive the award after Feng Zhang, who won the award in Biopharmaceutical Science in 2016 for his role in developing the CRISPR-Cas9 gene-editing system.

Since 2021, the MIT Environmental Solutions Journalism Fellowship has supported local and regional journalists in reporting high-impact news stories that connect climate change with local priorities. 

Now, the MIT Climate Project has published a report on the reach and impact of these fellowships, highlighting how the Institute’s scientific resources can help spark and deepen conversations about climate solutions in every corner of the country.

“Our goal is to offer trusted, grounded knowledge about climate change to everyone who wants to learn, so communities can make informed decisions for themselves about how to respond,” says Aaron Krol, who leads the Climate Change Engagement Program within the Climate Project. “Often, the best way to do that is just to lend support and scientific guidance to the people, like the reporters at local papers and radio stations, who know their audiences’ needs and perspectives best.”

Since the fellowship was founded, 20 journalists have completed the program, publishing 104 stories with a collective audience of nearly 3 million readers and listeners. Among the goals of the fellowship is to ensure that ambitious, long-form or serial climate reporting is not restricted to the large national outlets that can afford to maintain a climate desk. Americans consistently say they trust their local newsrooms more than national ones, and feel local news is an important institution in their cities and towns — making these news sources especially powerful media for introducing new ideas and perspectives on climate change and its solutions. 

MIT journalism fellows have covered the potential for offshore wind energy in Louisiana, flood preparedness in West Virginia, and the energy transition in Utah’s coal country, among many other topics with clear stakes for readers and their communities.

“Local journalists want to engage on climate issues,” says Krol. “Every year, we’re amazed by the quality of the applications we receive. There are so many reporters out there who know this is important, who have been holding onto ideas for stories, and just need that extra support to step outside their usual beats or devote the time and resources to these issues.”

The 20 outlets that have participated in the fellowship showcase the full variety of local news media in the United States today. Some are long-standing institutions in their cities and states, while others are recent startups trying out new, nonprofit models for local journalism in the 21st century. Some publish in print, some are online-only, and some report on the radio. Some have readerships in the hundreds of thousands, and others serve impactful niche audiences.

The most recent cohort of fellows, from 2025, exemplifies this range. At the Chicago Tribune, Karina Atkins reached hundreds of thousands of readers with her series on state and federal policies that have hampered Illinois farmers from diversifying their crops in preparation for a warming climate. Meanwhile, at Lancaster Farming, Carolyn Beans gave dairy farmers in Pennsylvania an in-depth look at the market for climate-smart milk.

“We don’t ask how big your audience is,” Krol says. “We ask who you’re going to reach, and how you’re going to connect climate change to their lives and livelihoods.”

MIT provides the fellows with editorial, scientific, design, and financial support. Fellows get a crash course in climate science from MIT experts, and work hands-on with interactive climate models to get new perspectives on policy and technology solutions. They also get access to a science editor who can supplement the work of the host newsroom with a specialized background in reporting and writing science-focused stories.

“The stories themselves are important, but I’m proudest of the difference our program has made for the careers of the journalists who have come through it,” says Krol. “We’ve had newsrooms dedicate more resources to following up on their climate stories, fellows pivot to energy and environment beats, outlets start using digital tools and data visualizations in new ways. We even had a fellow start her own newsroom to pursue more environmental and solutions reporting for Minnesota. Once these journalists get a chance to dig in on climate, they carry the knowledge and skills with them.”

Read the 2026 Impact Report to learn more about the MIT Environmental Solutions Journalism Fellows, and the impacts they made on communities across the country. All 100-plus stories published through the fellowship can be found on the MIT Climate Portal.

By harnessing the unique properties of quantum mechanics, scientists and engineers worldwide seek to enable systems with extraordinary capabilities. Many of them are working on the highly anticipated development of quantum computers capable of completing complex calculations at unprecedented speeds. These computers could meet the growing computational demands of both scientific research and data-intensive industries like finance, cybersecurity, and medicine.  

Necessary for quantum system development is an environment in which the fragile nature of quantum bits (qubits) is stabilized and the thermal noise (fluctuations in current/voltage) inherent in superconducting electronics is dampened. That environment requires cryogenic temperatures, those ranging from 5 to 10 millikelvins, colder than the extreme temperatures encountered in space. Dilution refrigerators create this needed cryogenic condition.

Dilution refrigerators used for quantum R&D need a wiring system that can operate in cryogenic temperatures, maintain a power-efficient direct current, and support high-speed data transmission. Researchers at MIT Lincoln Laboratory prototyped flexible, ribbon-like, low-frequency (LF) cables that not only meet these demands, but also are compatible with commercial circuit-board manufacturing processes. Maybell Quantum, a Colorado-based company supplying hardware for developing quantum systems, licensed the design for these cables and is adapting them for use in their dilution refrigerators.

"We’re planning to integrate Maybell LF CryoTrace, the ribbon wiring system transferred from MIT Lincoln Laboratory, across all thermal stages of our dilution refrigerators. Initially, the cables will be used for LF services, such as thermometry, heaters, and sensors, with feasibility studies planned for additional functions," says Lasse Nielsen, strategy and operations lead at Maybell Quantum. "After qualification testing, LF CryoTrace is planned for the next iteration of our internal wiring across the Maybell product family."

Motivation for invention

To support government initiatives in quantum computing, the Lincoln Laboratory research team investigated alternatives to conventional coaxial cables for use in hardware like dilution refrigerators. Coaxial cables can generate heavy heat loads for cryogenic hardware to address. And, as the number of qubits in quantum computers will increase, so will the number of coaxial cables in the infrastructure, making it difficult to fit stiff, bulky cable arrays into hardware supporting superconducting qubits.    

The team chose a stripline cable configuration with conductive layers positioned between flexible polymer layers that shield against electromagnetic interference (also known as crosstalk). Striplines offer consistency across different frequencies and minimal signal loss. The new cables were designed to accommodate large numbers of simultaneous signal transmissions; support direct-current operation without warming the cryogenic environment; and, importantly, provide easier integration into hardware than achievable with brittle coaxial cables.

"The main innovation is that the laboratory's cables can be fabricated by a traditional printed-circuit-board manufacturer. They're cheaper to fabricate and easier to install than traditional coaxial cables," says John Cummings, a principal investigator in the flexible cables project of the Lincoln Laboratory Quantum-Enabled Computation Group.

Citing ease of installation and durability as two factors making these cables attractive, Maybell Quantum says the ribbon format is mechanically robust, reducing handling-related breakages common with thin coaxials and improving repeatability in production. The supple flex cables allow assembly tasks that took days to complete to be done in a few hours.

"Over time, we think ribbonized, quantum-specific internal wiring can reshape manufacturing norms: faster and more consistent builds, easier field service, and more modular upgrades," Nielsen says.

Future outlook

Maybell Quantum is looking toward supporting quantum computing's transition from a laboratory-based capability to an industrial, commercially viable one. The huge gap between the current highly specialized quantum-laboratory environment and the robust infrastructure required for future industrial quantum computing lies in the hardware promoting the development of functional chips.

Maybell's mission is to develop reliable tools that commercial developers of quantum computers can use with ease and without the high costs and expert training associated with the equipment in today's quantum labs. The flex cables and Maybell's continued R&D into their capabilities and integration into various tools will foster a future infrastructure that could enable industry to scale manufacture of quantum computers to a level at which these powerful machines could cost-effectively find use in myriad enterprises.

"If you want to scale to hundreds of chips, you need interconnects that can handle more signals more reliably. That’s why the Lincoln Laboratory cables are so exciting for us — they enable true scalability," says Kyle Thompson, founder and chief technology officer of Maybell Quantum. "We believe this technology will materially improve our systems and strengthen the broader U.S. quantum ecosystem by moving federally funded innovation into American manufacturing."

From the icy expanse of the South Pole, John Della Costa, a researcher on the Background Imaging of Cosmic Extragalactic Polarization (BICEP) project, watches STS.042/8.225 (Einstein, Oppenheimer, Feynman: Physics in the 20th Century), a free online class from MIT Open Learning’s OpenCourseWare, as part of a weekly “Fysics Fridays” series he started with his team.

MIT Professor David Kaiser, who teaches the course, often receives thoughtful notes from remote learners, but says an email from Della Costa stood out.

“Hearing that John and his team are spending a part of their time with this course was just the best message to receive,” says Kaiser.

The BICEP collaboration uses a series of radio telescopes at the South Pole to study the cosmic microwave background — the oldest light, emitted about 380,000 years after the start of the universe. The team is looking for signs of primordial gravitational waves, which would help to support MIT Professor Alan Guth’s theory of cosmic inflation that explains the rapid early expansion of the universe.

“Inflation is really important in making sense of our observations of our universe,” says Della Costa. “We have yet to discover the evidence for inflation that definitively proves that it did happen, and BICEP’s main role here at the South Pole is to discover gravitational waves from the very early universe.”

Kaiser co-directs a research group on early-universe cosmology with Guth. He says he has colleagues who have worked as Antarctica winter-overs, and can appreciate the immense challenge of this work.

“It’s very exciting to see this important research flourishing,” says Kaiser. “It takes enormous effort and dedication.” 

Bringing Open Learning to the South Pole

Della Costa first discovered MIT OpenCourseWare, part of MIT Open Learning, as a graduate student at San Diego State University. At the time, the Covid-19 pandemic had altered his schedule and created more downtime to pursue additional independent learning. He was taking a nuclear physics course as part of his graduate program in astrophysics, and wanted to learn much more about the topic. A little bit of online research led to his discovery of class 22.01 (Introduction to Nuclear Engineering and Ionizing Radiation), taught by Professor Michael Short.

“I found the course so interesting, and I’ve been exploring OpenCourseWare ever since then,” says Della Costa.

Preparing to spend an entire year at the South Pole (from November 2025 to December 2026), he realized he would need a productive way to occupy his downtime and stay entertained while isolated from much of the world.

“The station is completely isolated. After a certain point, no planes can fly in because it’s too cold,” says Della Costa. “The station closed on February 14, and it will reopen at the end of October or early November, depending on the weather.”

Because internet access is so limited at the South Pole, he downloaded several courses ahead of time, including: STS.042/8.225, 8.02 (Physics II: Electricity and Magnetism), 8.03 (Physics III: Vibrations and Waves), and Guth’s course, 8.286 (The Early Universe).

Like Della Costa’s discovery of OpenCourseWare, STS.042/8.225 was rooted in the disruptive days of the Covid-19 pandemic. Kaiser had taught the course in its traditional, in-person format many times, until fall 2020, when the courses needed to be taught entirely remotely. He made slides and taught the course via Zoom — for synchronous and asynchronous learning — to approximately 100 students located throughout the world. The materials were initially posted on the course site. The online version was later refined and expanded, launching on OpenCourseWare in August 2022. Unlike many physics offerings, this course includes background readings by physicists, as well as historians, philosophers, and sociologists.

“In this course, we get to talk about some really amazing ideas from modern physics,” says Kaiser. “We start in the middle of the 19th century, still in an era of what we would now call classical physics, and we rapidly go through things like relativity, quantum theory, nuclear physics, and particle physics. We end up with some of my favorite material about cosmology and the Big Bang — the kinds of things that John and his team are actively working on right now from their perch at the South Pole.”

Building community and learning together

Beyond finding ways to stay occupied during downtime from his research, Della Costa realized the importance of engaging the 45-person community at the South Pole. He describes it as a tight-knit group that needs to work together and look out for one another, especially given the extreme isolation, cold, and darkness, which can take a serious toll on mental health during the winter months.

“It’s very important to have community activities here,” says Della Costa, who thought of the idea to launch the “Fysics Fridays” series a couple of months ago. 

The group gathers to watch lectures and documentaries about physics every Friday. The series kicked off with a documentary about atomic bombs, drawing strong interest from the very beginning. 

Della Costa realized that STS.042/8.225 would be an ideal offering for Fysics Fridays.

“I thought this would be a perfect lecture series for us to watch, because it’s fairly introductory,” says Della Costa. “Not everyone here is a physicist, actually. It’s widely accessible, but still meaty, and worth people’s time to watch.”

Team members have been very interested in watching the course, and they’ve also started doing experiments before watching the lectures. Della Costa says that they’ve done the double-slit experiment and plan to also make a cloud chamber to see cosmic rays going through it.

Now that Della Costa and Kaiser are in contact, Kaiser has made plans to provide a special Zoom colloquium for the community at the South Pole.

“This use of the course is especially inspiring,” says Kaiser. “It really speaks to the excellence and far reach of OpenCourseWare and Open Learning.”

An auto factory worker can remember the storage bin where she left a partly assembled component the night before, and quickly return to that spot to pick it up. But robots that may work side-by-side with her would struggle to develop and access this same type of “spatiotemporal” memory.

Now, MIT researchers have developed a long-term memory framework that allows robots to rapidly form and recall a detailed mental model of complicated, large-scale environments.

In the future, this advance could allow the factory worker to send a robotic assistant to fetch the item, simply by asking it to “go and grab the component we started assembling last night.”

This new method combines advanced map representations with rich descriptions of the environment that the robot gathers as it travels over a long period of time. The robot can quickly access this memory to answer complex queries about its environment in plain language.

This memory framework, which answers questions more accurately than state-of-the-art methods, runs fast enough for a mobile robot to use in real-time.

In addition to its potential uses in robotics, this method could have applications in augmented reality systems that aid maintenance workers in anomaly detection or assist commuters in wayfinding.

“If we want robots to work side-by-side with humans and interact better with humans, they must speak the same language. The robot must be able to reason about time and space the same way humans do. That is essentially what our method is doing. It is turning a traditional map into a language-based map that is easier for the robot to think about and access using language,” says Luca Carlone, an associate professor in MIT’s Department of Aeronautics and Astronautics (AeroAstro), principal investigator in the Laboratory for Information and Decision Systems (LIDS), and director of the MIT SPARK Laboratory.

He is joined on the paper by lead author Nicolas Gorlo, an MIT graduate student; and Lukas Schmid, a former research scientist at MIT and now professor at the University of Technology Nuremberg in Germany. The research was recently presented at the Conference on Computer Vision and Pattern Recognition (CVPR).

Spatiotemporal memory

Memory allows an artificial intelligence system, like a chatbot, to answer complex questions and reason about previous interactions with its user.

“We want to design a new type of memory, a spatiotemporal memory, that enables an AI-powered robot to remember real interactions and sensor observations. Like ChatGPT, but grounded in the real world and capable of answering any question about the environment, like ‘Where did I leave my wallet?’” Carlone says.

To develop such a memory framework, the MIT researchers bridged two lines of work: computer vision and robotic mapping.

Multimodal computer vision models can understand and richly describe the objects in a scene, but they often only process a single annotation at a time. On the other hand, robotic mapping frameworks create 3D maps of an environment, like an entire apartment or university campus, but usually lack detailed descriptions of objects or are computationally expensive.

The method the MIT researchers created, called Describe Anything, Anywhere, Anytime, at Any Moment (DAAAM), takes the best of both approaches.

Using DAAAM, as a robot traverses its environment, it attaches rich descriptions to objects it sees. For instance, the robot may note that a particular building on the MIT campus is called the Stata Center and is designed with a certain type of architecture, or that a bike rack holds five bicycles and the red one has a flat tire. 

It stores this detailed information in a 3D map-based representation that is arranged spatially, so objects will be grouped into separate regions. In this way, the robot can remember that the red bicycle with the flat tire is in the bike rack outside the Stata Center.

But existing techniques that capture such rich descriptions typically take a few seconds to annotate a few objects. This is too slow for real-time performance, since a robot might see hundreds of objects during a few minutes of exploration.

“The faster the robot can form this spatial memory, the more efficient it will be performing actions in the environment,” Carlone adds.

Streamlining the process

To speed things up, DAAAM aggregates nearby objects as it travels and uses an optimization method to select key frames to annotate. These are images with the clearest view of multiple objects, allowing the system to thoroughly describe several items in parallel, speeding up computation tenfold.

As the robot explores the space, it attaches each batch of annotations to multiple objects in a particular location on the 3D map.

“We annotate every object only once, so our framework can run in very large-scale environments in real time. And by clustering objects into regions, it can answer a wide range of queries about objects and locations in the environment,” Gorlo explains.

Once the system builds this spatial memory, it must retrieve information from an enormous database of objects and descriptions in an efficient manner. 

To enable this, the researchers used an LLM that calls on various tools, which can quickly retrieve specific information in a way that reduces hallucinations. This allows DAAAM to answer a user query accurately in only a few seconds. 

For instance, if one asks a robot about a certain sculpture it saw near an MIT campus building, DAAAM can use a semantic search tool to retrieve information based on the word “sculpture” or a different tool to retrieve information based on the location of the building.

When tested and compared with other methods, DAAAM was between 21 percent and 53 percent more accurate, depending on the question type. 

In the future, the researchers want to expand DAAAM so the system can capture significant events that happened in the environment. They are also working to incorporate confidence levels into the system’s responses.

“Ultimately, we want to have robots that can help with any sort of tasks. With this framework, we are trying to create the foundations to enable a generalist agent that can do anything you ask,” Gorlo says.

This research was funded, in part, by the U.S. Army Research Laboratory and the Office of Naval Research. Carlone is currently on sabbatical as an Amazon Scholar; this article describes work performed at MIT and is not associated with Amazon.

In May, the Initiative for New Manufacturing (INM) marked its first anniversary with MIT Manufacturing Week, four days of events that attracted more than 800 registrants including students, faculty, industry leaders, investors, entrepreneurs, and government officials to explore topics ranging from how companies are using AI on factory floors to the role of startups in introducing innovation to new workforce solutions to address the worker shortage.

“INM launched a year ago with the premise that strengthening the industrial base needed a coordinated response, and MIT has a responsibility to lead it,” says Paula T. Hammond, dean of MIT’s School of Engineering and co-chair of INM’s Steering Committee. “The response and participation level has been huge. MIT Manufacturing Week proved that the appetite for change — from students to chief executives — is real and urgent.”

The week opened with a cybersecurity workshop co-led by INM and Google Cloud for the initiative’s industry members. It continued with the MIT MIMO (Machine Intelligence for Manufacturing Operations) symposium focused on deploying artificial intelligence on factory floors, alongside discussions on workforce development, emerging technologies, startups, and industrial transformation. The week closed with a regional research showcase and competition that drew more than 140 graduate students and postdocs from across New England.

Over the past year, INM has also continued its distinguished speaker series featuring manufacturing leaders including Keith Flynn, senior vice president of manufacturing at Anduril; Roland Busch, president and CEO of Siemens; and Venky Alagirisamy, COO of Nike.

Inspiring a new generation of manufacturing startups

A central goal of INM is to help more students see manufacturing as a frontier for scientific discovery, technological innovation, entrepreneurship, and societal impact.

To support that effort, INM is launching and leading programs to help move early-stage ideas and new technologies from the lab to real-world development, and to catalyze new manufacturing companies. 

This year, INM partnered with NSF I-Corps New England, which helps researchers turn their startup ideas into companies, to host its first manufacturing research showcase. More than 140 teams from 17 universities across New England applied to participate. Forty finalist teams received mentorship on their ideas and advanced to the final competition, where eight teams shared $50,000 in prize funding.

The top prize in the category “most transformative innovation” went to MIT PhD student Jake Read for “The End of G Code,” a project focused on modular machine control architectures designed to accelerate the development of new manufacturing equipment and processes. Vatsal Patel from MIT and Joshua Grace from Yale University won the top prize in the research excellence category, for “VisFT,” scalable six-axis force-torque sensors.

Project themes presented by participating teams included AI tools for manufacturing, semiconductor manufacturing and process control, robotics and autonomous assembly, digital twins and simulation, new materials, additive manufacturing, next-generation shipbuilding, and biomanufacturing. 

“Entrepreneurship is a transformative pathway to take research to market, and to drive faster innovation and scale-up,” says John Hart, INM faculty co-director and head of MIT’s Department of Mechanical Engineering. “At INM’s inaugural research showcase, we had tremendous interest from universities across New England, along with enthusiastic participation from industry, investors, and experienced founders across the ecosystem. We are excited to build on this success and work toward a nationwide program and platform for entrepreneurship and translation in manufacturing.” 

The Cheng Wu Foundation supported the showcase. 

Growing industry membership

During MIT Manufacturing Week, First Solar became INM’s eighth industry member, joining Amgen, Autodesk, GE Vernova, Flex, PTC, Sanofi and Siemens. 

The growth of INM’s consortium reflects a broader recognition that the challenges facing modern manufacturing — from supply chain resilience to workforce development and industrial competitiveness — are too complex for any single sector or company to address alone. 

This reflects renewed interest in manufacturing at a moment when advances in artificial intelligence, robotics, energy systems, and advanced materials are transforming industrial production. INM provides a platform to convene and provide solutions.

INM’s industry consortium model brings industry, researchers, and educators together around shared manufacturing challenges, with a focus on emerging technologies, workforce transformation, and commercialization pathways. Members participate in workshops and working groups on topics including cybersecurity and digital twins, implementing automated systems, AI agents in regulatory environments, and AI and continuous innovation. INM helps them connect with students, meet with startups, and learn from one another.

“Our members see MIT as a partner that can help them both address today’s challenges and think far into the future,” says Rick Locke, dean of the MIT Sloan School of Management and co-chair of INM’s steering committee. “This kind of multi-industry engagement is unusual and powerful.”

A year of rapid progress

When MIT launched INM a year ago, the goal was to create stronger connections between research, industry, workforce development, and entrepreneurship — helping accelerate how new manufacturing technologies move from the laboratory into real-world development.

Since then, the initiative has expanded quickly across research, industry, workforce training, and student engagement. INM issued a call for proposals focused on artificial intelligence and automation, receiving an incredible response from faculty and researchers, and funding eight seed research projects. In June, the initiative plans to publish eight white papers as part of a broader study examining the future of manufacturing. 

During MIT’s Independent Activities Period (IAP) in January 2026, INM collaborated with NSF I-Corps to guide 13 early-stage teams through customer discovery as part of the I-Corps Spark program.

Workforce development has also been a major focus. This fall, MIT launched the Technologist Advanced Manufacturing Program (TechAMP), led by Principal Research Scientist John Liu, to create a new generation of shop floor leaders and drivers of productivity — becoming“‘technologists” — at six sites across New England, including three community colleges. 

“INM has the potential to transform the national manufacturing workforce,” says Liu. “It will require deep engagement between how people learn and lead, and how firms adopt new technologies and transform. We’re just getting started.” 

INM is now exploring a national rollout of TechAMP, along with expansion into areas including biomanufacturing and semiconductor manufacturing.

On campus, INM supported student engagements including an AI and automation lunch series that Professor Faez Ahmed and colleagues organized, and visited factories through its Factory Observatory program that Ben Armstrong and the MIT Industrial Performance Center led. This spring, students also founded MIT’s first manufacturing club, holding its launch event during MIT Manufacturing Week. “We’re thrilled students are taking the lead,” says Sloan associate professor and INM faculty co-director Karen Zheng. “It was really exciting to see a full room of 80-plus students across campus coming together for the kickoff event during the busiest final period of a semester. This speaks to the students’ enthusiasm.” 

An eye toward the long term

While maintaining a deep focus on strengthening domestic manufacturing, INM aims to have a global reach. For example, the initiative is collaborating with NAMTECH, a new education institute in Ahmedabad, India, where students are now taking an adaptation of MIT’s well-known “yo-yo course,” or 2.008 (Design and Manufacturing II), focused on the fundamentals of manufacturing processes.

Next year, INM plans to bring more manufacturing leaders to campus, offer additional programming for emerging entrepreneurs, graduate the first cohort of TechAMP students, bring TechAMP to new states, grow the consortium to include new industries, and deepen research into manufacturing productivity. 

“INM aims to be a catalyst for transforming manufacturing across the nation to drive innovation, economic growth, and new types of jobs,” says Chris Love, faculty co-director of INM. “MIT’s work on the PIE (Production in the Innovation Economy) study in 2013 highlighted the value of proximity between production and innovation. INM seeks to rekindle this relationship in manufacturing across the country.”

In 2026, MIT granted tenure to 10 faculty members across the School of Engineering. This year’s tenured engineers hold appointments in the departments of Aeronautics and Astronautics, Civil and Environmental Engineering, Electrical Engineering and Computer Science (EECS) — which reports jointly to the School of Engineering and MIT Schwarzman College of Computing — and Mechanical Engineering, as well as within the Institute for Medical Engineering and Sciences (IMES).

“I’m delighted to congratulate the 10 newest tenured faculty members in the School of Engineering. This major career milestone reflects not only their impact and excellence in research, but their deep commitment to education and mentoring the next generation of engineers. I am so excited to see what new developments, innovations, and technologies will come next from this incredibly accomplished group,” says Paula T. Hammond ’84, PhD ’93, dean of engineering, Institute Professor, and professor of chemical engineering.

This year’s newly tenured engineering faculty include the following:

Jacob Andreas is an associate professor in EECS and is affiliated with the Computer Science and Artificial Intelligence Laboratory (CSAIL). His work is in natural language processing, and more broadly in AI. He aims to understand the computational foundations of language learning, and to build intelligent systems that can learn from human guidance.

Zachary Cordero is the Esther and Harold E. Edgerton Associate Professor in the Department of Aeronautics and Astronautics and the associate director of the MIT Gas Turbine Laboratory. His research seeks to enable frontier aviation and space platforms through advanced materials, manufacturing, and structures, with a particular focus on high-temperature systems.

Christina Delimitrou is the KDD Career Development Professor in Communications and Technology and an associate professor in EECS. She is also affiliated with CSAIL. Her research sits at the intersection of computer architecture and computer systems; specifically, she is one of the first systems researchers to apply machine learning techniques to design and management problems in the cloud.

Sili Deng is the Doherty Career Development Professor in Ocean Utilization and an associate professor in the Department of Mechanical Engineering. Her group develops scientific machine learning and experimental approaches to understand, predict, and engineer chemically reacting systems for sustainable energy, advanced materials manufacturing, and climate-resilient technologies.

David Des Marais is the Amgen Career Development Professor in the Department of Civil and Environmental Engineering. He leads the Des Marais Lab, whose primary focus of research is to understand the mechanisms of plant-environment interaction, using tools from molecular, quantitative, and population genetics to identify the physiological basis of plant response to environmental cues.

Carmen Guerra-Garcia is the Esther and Harold E. Edgerton Associate Professor in the Department of Aeronautics and Astronautics and the director of the Aerospace Plasma Group. Her work lies at the intersection of aerospace engineering, low-temperature plasma technologies, and gas discharge physics. It addresses two aviation challenges — reducing emissions, and ensuring safety of next-generation aircraft — through three interconnected thrusts: advancing the fundamental science of electrical discharges in flowing gases and nonuniform media, applying that science to plasma-assisted combustion and chemical conversion, and developing physics-based approaches to lightning protection.

Laura Lewis is the Athinoula A. Martinos Associate Professor in EECS and IMES. Her research aims to develop methods to analyze and interpret multi-modal neuroimaging data in order to enable measurement of previously undetectable aspects of brain function. She has a particular interest in fast fMRI, EEG, and PET, and is applying those methods to study sleep.

Tami Lieberman is the Hermann L. F. von Helmholtz Career Development Professor in the Department of Civil and Environmental Engineering and IMES. She leads the Lieberman Lab, which seeks to understand how ecology and evolution shape the personalized communities of the human microbiome, and the role of this personalization on human health.

Kevin O’Brien is an associate professor in EECS and a member of the Research Laboratory of Electronics.  He leads the Quantum Coherent Electronics Group. His research efforts focus on developing tools, techniques, and devices to enhance the measurement of quantum systems, most notably superconducting quantum computers.

Wim van Rees is an associate professor in the Department of Mechanical Engineering and the Leonardo Career Development Professor in Engineering. His research advances high-order, high-fidelity numerical methods for efficiently simulating interactions between fluid flows and moving or deforming bodies, with methodologies spanning applications from wake vortex dynamics to bio-inspired propulsion and morphing structures. 

Researchers around the world are racing to develop new quantum-based systems for sensing, communication, computing, and control that have the promise of outperforming traditional systems. Creating stable, measurable, distinguishable quantum states, which would be the heart of any such system, is a daunting task.

Quantum states possess unique properties that can be exploited for developing novel information processing systems. Two key properties, stability and distinguishability, are hard to achieve, however. Extracting information from a quantum system depends on the distinguishability of quantum states, an intrinsic property associated with a property known as orthogonality. Nevertheless, no two Gaussian states (a widely studied class of quantum states) are orthogonal, and this yields an unavoidable error when attempting to distinguish them. 

In addition, present quantum devices tend to remain stable only for a fraction of a second, and require complex protocols to distinguish states. Now, researchers at MIT and the University of Ferrara have found a new approach for creating easily distinguishable states that could help to enable the development of these new quantum-based devices.

The new approach is described in a paper published today in the journal Physical Review A, by Moe Z. Win and Peter L. Falb at MIT with Andrea Giani and Andrea Conti at the University of Ferrara. The team found a way of translating between quantum states of light and algebraic varieties (a mathematical structure from abstract algebra), making the analysis more manageable by reducing it to solvable mathematical equations.

“Quantum systems can provide performance that is significantly better than classical counterparts,” Win says, “but this doesn’t come for free.” To develop practical devices for producing and detecting different states, “one needs to carefully engineer the quantum states in which they encode information.” 

Traditional computers typically use different voltages in a solid-state device to encode ones and zeros, while optical systems may use the presence or absence of a pulse of light. In quantum devices, the states might have to do with the spin state of a single atom, or the excitation level of a group of electrons.

Win adds that “we have been studying how to design distinguishable quantum states, which translates directly into improved performance for sensing and communication.” In the jargon of the field, they are improving the orthogonality — that is, the distinguishability — of different states.

The particular kinds of states studied in this theoretical analysis had to do with energy levels of photons, or particles of light. Giani explains that they used an operation called photon variation. This can take two forms: photon addition, in which photons are excited to a higher energy state, or photon subtraction, in which photons are annihilated (i.e., removed from the system). These operations change the quantum state from Gaussian to non-Gaussian states; it’s the non-Gaussian states that seem most useful, the team concluded. 

“The domain of non-Gaussian states is quite big,” Giani says, “but among them, we are looking into non-Gaussian states that are easier to implement with current technologies, because if we want to make the transition to the quantum world, we need to take into account realistic experimental challenges.”

Unlike some kinds of cutting-edge technologies being studied for possible quantum applications, Giani explains, “these kinds of photon-varied states have already been produced in the laboratory, and there is much interest in this kind of operation.”

These types of states are relatively new, Conti says, and so “there was a need for a theoretical characterization for these states,” The theoretical characterization this team derived, based on underlying mathematical properties, makes it possible to design states with higher levels of distinguishability. 

With this work, Win says, “we have a theory that gives us a blueprint to go design these non-Gaussian states, rather than just, ‘try this and that, and let’s hope they’re somewhat distinguishable.’ Our theory tells us exactly how to go about designing orthogonal non-Gaussian states.”

The findings result from the connection between the algebraic equations and the underlying physics, Win says, “That was the important connection between different disciplines — bringing algebraic geometry to the table.” 

“The equations to be solved for determining the orthogonality” of the quantum states “happened to be polynomial equations,” Falb says. “It just happened that there was the appropriate mathematics to solve them.”

Now that the principles have been established through this work, implementation should be relatively straightforward, the researchers say. There already are some optical setups that can be used to implement these kinds of states. 

“In principle,” Giani notes, “you can just put the parameters that you find by solving these equations directly into your physical apparatuses and produce these kinds of states. I don’t think this requires some more-advanced technology.” 

Conti adds that “as soon as this paper is published, we hope that experimentalists can try these methods.”

But that’s just the beginning, Win emphasizes. “We are getting momentum, and it’s very exciting,” he says. “The approach that we are taking here is to ask more general questions than just, ‘here’s a particular setup, how do you tune it to get a performance gain?’ Rather, we’re looking at a class of signal design problems, and then finding keys that really unlock these, so that hopefully the answer will not just be applied to only one particular setup, but something significantly broader.”

An international team of researchers has developed a novel fluorescent nanosensor powered by carbon nanotubes that is capable of rapidly detecting an emerging biomarker linked to gut health and disease. 

This important development could eventually lead to faster and more accessible gut-health testing. 

Indole-3-propionic acid (IPA) is a metabolite produced by gut bacteria during the breakdown of dietary tryptophan, an amino acid essential for protein synthesis. It plays an important role in regulating inflammation and oxidative stress, and has been associated with conditions such as inflammatory bowel disease (IBD), Type 2 diabetes, and liver disease. However, current detection methods rely on traditional mass spectrometry-based analytical techniques, which are costly and time-consuming, making it impractical for routine screening or point-of-care use.

The new platform addresses a longstanding gap in gut metabolite sensing. Using a fluorescence-based approach, the sensor produces a rapid optical readout within minutes, offering a significantly faster and more accessible alternative to conventional analytical techniques. It demonstrates high selectivity, distinguishing IPA from closely related metabolites commonly found in the gut, which enables accurate detection even in complex biological environments such as blood serum.

“This is the first time we are able to directly and rapidly measure IPA levels in biological samples using an optical nanosensor,” says co-first author Mervin Ang, assistant professor at the National Institute of Education (NIE) within Nanyang Technological University in Singapore, who was also associate scientific director at the Disruptive and Sustainable Technologies for Agricultural Precision (DiSTAP) interdisciplinary research group within the Singapore-MIT Alliance for Research and Technology (SMART) when the research was initiated. “This novel approach, which moves away from traditional mass spectrometry, can pave the way towards faster and more accessible ways of monitoring gut health in real-world settings.”

This latest breakthrough is described in the research team’s open-access paper, “Fluorescent Nanosensor for Indole-3-Propionic Acid Detection in Gut Health Monitoring,” in the journal Advanced Healthcare Materials. The work was led by researchers at NIE, MIT, and SMART, in collaboration with clinicians from the National University Hospital (NUH) and Yong Loo Lin School of Medicine within the National University of Singapore (NUS Medicine). 

From monitoring plants to sensing human health

The new nanosensor builds on SMART DiSTAP’s research into nano and optical sensor technologies. Originally developed to monitor plant health — including plant growth signals and stress responses —  the technology has now been adapted for human health applications by redesigning the nano- and optical-sensing platform to detect IPA.

“This work builds on technology at SMART DiSTAP on molecular recognition. We have used techniques like this to measure hormones and metabolites in living plants for agriculture, and have now applied it to the human gastrointestinal system. We were able to apply it to this long-standing challenge in gut health,” says Michael Strano, SMART DiSTAP lead principal investigator, the Carbon P. Dubbs Professor of Chemical Engineering at MIT, and corresponding author. 

“By focusing our molecular recognition on this important gut health biomarker, we’ve demonstrated a powerful new tool that could one day enable proactive, personalized health care. The tool promises near-instant insights into gut wellness, or the status of chronic diseases like IBD.”

A dual-mode platform for rapid testing and future monitoring

A key innovation of the technology is its dual-mode sensing capability. 

The nanosensor operates in both a visible fluorescence mode, enabling rapid, low-cost, high-throughput screening of biological samples; and a near-infrared mode, with wavelengths that can penetrate deeper into tissues. The near-infrared capability, enabled by carbon nanotubes, allows the technology to be adapted for in vivo applications and integration into wearable devices that could be used for home-based testing or continuous monitoring. This could, for example, help patients with chronic conditions like IBD detect flare-ups earlier and manage their health with greater autonomy. 

This flexibility allows the platform to be utilized in various environments, from laboratory tests to hospital bedside use, and wearable devices for real-time health monitoring. 

Validated in patient samples

To evaluate its clinical relevance, the research team collaborated with NUH clinicians to test the nanosensor on 125 human plasma samples across multiple patient groups, including healthy individuals and those with gastrointestinal diseases.

The study revealed significant differences in IPA levels between healthy individuals and patients with inflammatory bowel diseases, including Crohn’s disease and ulcerative colitis. Patients with active gut inflammation showed lower IPA levels — consistent with established clinical findings.

“From a clinical perspective, having a rapid and minimally complex way to assess metabolite levels like IPA could be very valuable,” says Jonathan Lee, senior consultant in the Division of Gastroenterology and Hepatology within the Department of Medicine at NUH; adjunct associate professor at NUS Medicine; and co-first author of the work. “It has the potential to complement existing diagnostic tools and provide additional insights into patients with inflammatory bowel diseases.”

Faster, more accessible gut health testing

Beyond the laboratory, this research could pave the way for faster and more accessible gut health testing. Instead of relying on complex and time-intensive laboratory methods, the new nanosensor could enable rapid screening in clinics, or even portable or home-based testing, helping to detect gut diseases earlier and monitor treatment progress more easily.

Unlike conventional microbiome tests that focus on identifying which bacteria are present, this nanosensor measures what those microbes are actively producing, offering a more direct and functional snapshot of gut health. Directly measuring metabolite output, rather than bacterial composition alone, could provide more meaningful insights into overall health and support more personalized approaches to health care. 

Beyond clinical diagnostics, the technology can be used to track the immediate efficacy of dietary interventions. Users can see rapidly if specific foods or probiotics are successfully fueling their gut bacteria to produce anti-inflammatory molecules like IPA. The sensor also demonstrated reliable performance in complex biological fluids such as serum and plasma, an important step toward real-world clinical deployment and further translational applications. 

For pharmaceutical and therapeutic research, the nanosensor could be used to conduct rapid functional tests to determine the efficacy of new therapeutics or probiotics. By providing an instant readout of IPA levels, the platform could enable them to demonstrate in real time that their therapeutics are biologically active and effective, significantly accelerating drug screening and dosage optimization processes.

Toward point-of-care diagnostics, and beyond

“The transition from laboratory discovery to a point-of-care clinical tool is already underway,” says Ang. “With further development, the platform has the potential to be translated into clinical applications, and in the long term, adapted into portable platforms for routine health monitoring.”

Looking ahead, the research team has been awarded an Innovation to Startup Innovation Grant to incubate a Singapore proto-startup to advance validation and development. The focus would be to translate the sensor into a point-of-care clinical diagnostic tool, and aim to expand the platform to detect multiple gut metabolites simultaneously and AI-driven signal deconvolution, enabling more accurate, comprehensive and personalized gut health monitoring. 

Future developments may also explore integration into wearable devices, microneedle systems, or microfluidic platforms for continuous, real-time sensing.

The research was supported by the Intra-CREATE Seed Collaboration Grant, and research conducted at SMART was supported by the National Research Foundation Singapore under its Campus for Research Excellence and Technological Enterprise (CREATE) program.

In a hospital or at home, temperatures are usually taken using an oral or forehead thermometer, but these do not always accurately reflect the core body temperature. Measuring core temperature from within the body could make it easier to determine whether someone is sick, and whether they’re at risk of spiking a dangerous fever.

To make it more feasible to obtain core body temperature measurements, MIT engineers have developed an ingestible sensor that can send continuous temperature updates from the GI tract. 

The sensor is shaped like a tiny blueberry, 6 millimeters in diameter and 4 millimeters in height. That makes it much smaller than existing ingestible temperature sensors, which are more difficult to swallow and pose a potential risk of obstructing the GI tract.

“A sensor like this gives us the ability to monitor infections and identify them early,” says Giovanni Traverso, an associate professor of mechanical engineering at MIT, a gastroenterologist at Brigham and Women’s Hospital, and an associate member of the Broad Institute of MIT and Harvard. “That’s very relevant, particularly for at-risk populations like people who are immunosuppressed from chemotherapy treatments or immunosuppressive drugs.”

Ingestible sensors could also enable more accurate temperature measurements for fertility tracking, and for monitoring people during anesthesia.

Traverso and Anantha Chandrakasan, MIT’s provost and the Vannevar Bush Professor of Electrical Engineering and Computer Science, are the senior authors of the new study. MIT postdoc Saransh Sharma is the lead author of the paper, which appears today in Nature Electronics.

Ingestible electronics

A handful of ingestible temperature sensors have become commercially available in recent years, but most are the size of a multivitamin or slightly larger, making them more challenging to swallow. Their size can also increase the risk of obstructing the GI tract.

Those capsules tend to be large due to the complex circuits they include, which require a great deal of power. That power is provided by relatively large, on-board batteries that make up much of the bulk of the capsule.

The MIT team wanted to design sensors that could measure temperature accurately, but at a much smaller size.

“The reason for them to be small is safety,” Traverso says. “We want something that is so small that the risk of any blockage or obstruction is highly mitigated, and also so that it can be easily ingested.”

To create a smaller device, the researchers set out to reduce the size of all of the main components — the temperature-sensing circuit, the antenna that relays temperature data, and the battery.

For the circuit, they created their own customized circuit that can fit onto a 1-square-millimeter silicon chip. To reduce the chip’s power consumption, the researchers designed an oscillator based on leakage current — the small current that flows through a circuit when it’s off. The frequency of this current varies depending on the temperature of the chip’s surroundings.

This circuit, which can detect temperature with an accuracy of 0.01 degrees Celsius, requires very little power — about 10 nanowatts. This means that it can be powered with a 1.55-volt coin cell battery, which is 4.8 millimeters in diameter and about 1.6 millimeter thick.

The new design further cuts energy consumption by using a communication strategy known as backscattering. This approach allows most of the power requirements to be outsourced to an external antenna that is located outside the body, within a foot or two of the sensor. The external antenna emits an ultra-high-frequency radio wave, which is then modulated by a tiny antenna within the sensor and sent back to the external antenna. By interpreting the changes in the radio wave, the external antenna can calculate the temperature value.

“We combined all of these different pieces together — the silicon chip, the battery, and the antenna — and we made it into an ingestible capsule, which is the smallest ingestible capsule that we have seen for temperature-sensing paradigms,” Sharma says. 

The internal antenna sends out a temperature reading once every second, allowing for continuous monitoring of temperature.

Tiny thermometers

The researchers envision that this kind of sensor could be useful in several scenarios, including monitoring infection and observing patients during and after anesthesia. Anesthesia often disrupts the body’s normal temperature regulation mechanisms, which can put patients at risk of hypothermia.

This type of device could also be used at home, for monitoring fevers in children, or measuring core body temperature as a marker of ovulation, for fertility purposes. It could also be useful for monitoring athletes, soldiers, or anyone else who might be exposed to extreme temperatures. 

To explore these possible uses, the researchers tested the sensors in animals while they were under anesthesia, and found that they could accurately detect and transmit temperature information. They also obtained accurate readings from animals that were awake and actively moving.

The researchers are now working on combining the temperature sensor with other sensors that could measure vital signs such as heart rate. They hope to begin testing these types of sensors in clinical trials within the next few years. 

If proven effective for people in high-risk situations, Traverso believes such sensors could become widely used by anyone who needs to monitor their temperature. 

“I think this could replace all thermometers, because it’s the most accurate way of taking temperature,” he says. “If we have miniature systems that can be easily swallowed and give very accurate data that’s superior to the current data, I think it can be helpful in so many ways.”

Other authors of the paper include Yubin Cai, Injoo Moon, Zhenming Yang, Peter Chai, Niora Fabian, Kailyn Schmidt, Alison Hayward, Andrew Pettinari, Maria Platero, Benedict Laidlaw, and Ashley Guevara.

The research was funded by the 711th Human Performance Wing, the Defense Advanced Research Projects Agency (DARPA), and the Advanced Research Projects Agency for Health (ARPA-H), which notes that the views and conclusions contained in this article are those of the authors and should not be interpreted as representing the official policies, either expressed or implied, of the United States government.

Examples of actions MIT has taken since 2023 to address concerns of antisemitism

• MIT President Sally Kornbluth and other senior leaders have sent multiple campus-wide letters and video messages condemning reports of antisemitism on campus. 
• Prior to October 7, MIT joined the Hillel Campus Climate Initiative, which helps universities build awareness of and take action against antisemitism. Learnings from that engagement continue to guide MIT’s campus response. 
• MIT increased security around campus, including at the Office of Religious, Spiritual, and Ethical Life building, which houses MIT Hillel.
• MIT participated in the Brandeis Leadership Symposium on Antisemitism in Higher Education.
• MIT created multiple opportunities for training, education, and dialogue, e.g.: 
  • American Jewish Committee training on antisemitism for Academic Council, which comprises the Institute’s senior leadership 
  • ADL training on antisemitism for MIT’s Bias Response Team 
  • Institute-level educational programming, including an event featuring Professor Pamela Nadell—director of the Jewish Studies Program at American University and a scholar of antisemitism in America
• The Institute updated, publicized, and enforced its policies on protests and demonstrations and posters/displays.
• MIT helped create and provided financial support for two years of weekly lunches focused on supporting MIT’s Jewish community.
• MIT provided support for the faculty-created MIT-Kalaniyot program, which brings Israel-based faculty and postdocs to MIT with the intent of building and strengthening ties between Israeli researchers and the MIT community.
• The Institute established a cross-functional team with representatives from the Institute Discrimination and Harassment Response Office (IDHR), Office of Student Conduct and Community Standards (OSCCS), Division of Student Life, Human Resources, and the Office of General Counsel to promptly and fairly triage reports of antisemitism and other forms of bias relating to the conflict in the Middle East. 
• Instituted disciplinary proceedings for policy violations stemming from campus protests and related activities, which resulted in significant sanctions for a number of students, including suspensions, expulsions, and numerous individual bans from being on campus, as well as permanent derecognition of a student organization. 
• And MIT established a Title VI coordinator.

Student discipline process improvements

Apart from individual student discipline cases as described above, MIT conducted a holistic review of its student discipline process, which resulted in a number of policy and procedure changes, including: 

• The senior administration has a more direct role in reviewing significant student discipline cases, with the Vice Chancellor for Student Life regularly conferring with the Chair of the Committee on Discipline (COD) and participating in hearing panels in serious cases. 
• The role of the Senior Associate Dean of Student Conduct and Community Standards has been enhanced and elevated, reporting directly to the Vice Chancellor for Student Life. 
• A more streamlined process allows the Chair of the COD to take action in response to noncompliance with previous COD sanctions.
• Additional sanctions were added to the COD Rules, giving the COD a broader range of tools to address student misconduct.
• Enhanced training on discriminatory harassment were made available to COD members. 

Over the last couple years, MIT has experienced a significant decline in the number of reports of student misconduct arising out of allegations of antisemitism or other forms of bias based on religion or ethnic/national origin. 

Courts have dismissed lawsuits claiming antisemitism at MIT

As a result of MIT’s actions, including specifically some of those described above, federal courts have dismissed claims of antisemitic harassment and discrimination asserted against MIT under Title VI. In doing so, the courts have acknowledged the escalating steps MIT has taken to promote a safe, inclusive community for its Jewish community members. For example, in a unanimous decision by the First Circuit Court of Appeals holding that MIT satisfied its Title VI obligations, the Court noted:   

• “As the protest gatherings occurred over the course of seven months, culminating in the Kresge Lawn encampment, MIT took an escalating series of actions aimed at calming the turmoil without violence… Even if we accept plaintiffs' position that some conduct of some protestors was antisemitic, that would not provide a Title VI pretext for requiring MIT to eliminate the protests entirely. In that respect, by managing the situation so as to avoid escalation and violence, MIT was much more effective than plaintiffs claim.” 
• “[A]ny reasonable school administrator in MIT's position could have reasonably surmised that its progressively evolving responses prevented the on-campus conflict from exploding into real violence between October 2023 and May 2024.”

Importantly, MIT took these steps to protect the MIT community even while the Court concluded that much of the campus protest activity at MIT amounted to legally protected expression and not a violation of Title VI: 

• “This absence of consensus reflects ongoing debate as to the relationship between anti-Zionism and antisemitism – debate that our constitutional scheme resolves through discourse, not judicial fiat. Indeed, the debate on occasion has been formal and high profile…We decline to interpret Title VI as arming either side of that debate with the powers of a censor.”

2026 Quality of Life survey results

Jewish student sentiment has significantly improved and is now higher than the general MIT student population. 

Below are data from the spring 2026 Quality of Life survey, a community-wide survey administered every two years to better understand the lives of faculty, staff, postdoctoral scholars, and students. The data reflect responses from those who selected “Judaism” as their religion, alone or in part (respondents were able to select more than one religion).

Overall, how satisfied are you being a student at MIT? 
(Percentages are a sum of respondents who selected “very satisfied” + “somewhat satisfied”)

Jewish Undergraduates:
2024: 87%
2026: 97% (compared to 86% for all undergraduate students) 

Jewish Graduate Students:
2024: 78%
2026: 94% (compared to 88% for all graduate students)

I feel that I belong at MIT. 
(Percentages are a sum of respondents who selected “strongly agree” or “somewhat agree”)

Jewish Undergraduates
2024: 83%
2026: 92% (compared to 80% for all undergraduate students)

Jewish Graduate Students 
2024: 70%
2026: 79% (compared to 79% for all graduate students)

Notably, not a single Jewish undergraduate respondent in 2026 disagreed with the statement “I feel that I belong at MIT.”

In winter 1997, at age 60, when many researchers might be looking forward to retirement, Harriet Latham Robinson SM ’61, PhD ’65 was pursuing a faculty position as the chief of microbiology and immunology at the Yerkes National Primate Research Center at Emory University in Atlanta, Georgia. 

She got the job. 

There, she would also co-found GeoVax, a biotechnology company, based on her preclinical research, including work on developing an HIV-1 vaccine. 

Often, as the only woman in a room throughout much of her career, and in the still-developing and male-dominated field of molecular biology, her colleagues were referred to as “doctor” or “professor” at scientific symposia and committee meetings. 

“In contrast,” she recalls, “I was Harriet.”

Becoming a scientist

Robinson was born in 1938, the second of four children, to a mother, Ruth, and a father, Allen, from Ohio and Connecticut, respectively. After finishing grammar school, she attended the Girls’ Latin School, a public magnet school for college-bound young women. Although the school offered only two classes in science — one semester of chemistry and a health class — Robinson credits her time there for inspiring a lifelong love of learning, especially history and languages. 

“At our 50th and 60th high school reunions, I was struck by what my Girls’ Latin school classmates had done with their lives,” she says. “We had become not only wives, mothers, teachers, and nurses we were supposed to become, but also physicians, lawyers, professors, politicians, and businesswomen.” 

Robinson pursued her undergraduate studies at Swarthmore College, where she intended to study political science. After an introductory biology course, however, she switched her major. Despite the shift, a love of languages persisted: Robinson took Russian and, the summer after her senior year of college, served as a Russian-English speaking guide at the 1959 American National Exhibition in Moscow. Despite mounting tensions between the United States and the Soviet Union, she served again in a similar role from September 1961 to January 1962 for a traveling transportation exhibition in Russia and Ukraine, where she was stationed by a Ford Thunderbird, wearing a TWA stewardess uniform.

“We were true entertainment, as well as education, and I worked to do my best to answer questions about America,” she says. “I was most surprised by the pride the Russian people took in the post-World War II accomplishments of their country.” 

Robinson might not have had a career in science at all had it not been for a dean at Radcliffe College who recognized Robinson’s interest in science. Robinson had thought it appropriate, as a young lady, to pursue marriage and to only further her education to become a teacher or nurse. Seeking permission to take chemistry instead of education courses to fulfill requirements for getting a teaching degree, she was referred to a dean who considered it perfectly appropriate for a young woman to pursue another career. Robinson recalls that the dean declared, “My dear, you want to be a scientist.” 

The foundation for a career

Robinson was soon accepted at MIT and was offered a fellowship to teach in an introductory biology lab to help pay her way. She returned from Moscow just five days before the start of a master’s program in biochemistry. In the Department of Biology at MIT, there were only a handful of women, no female faculty, and few ladies’ rooms in 1959. 

It was there that she met Walter “Wally” J.K. Tannenberg, a onetime partner but lifelong friend and companion, an MD taking courses at MIT. He wasn’t “at all taken aback by my becoming an educated woman,” Robinson says. He taught her to ski, and they sailed his lightening, the Ondine, in circles around Robinson’s parents’ comparatively slow motor sailor, the Palometa. 

Their breakup just before the winter holidays in 1963 precipitated her reentry to graduate school, to pursue her thesis work in the lab of Jim Darnell; she threw herself into studies to sit a qualifying exam less than a month after reentry. 

“A Bell Labs physicist who had just joined the Darnell Lab opined that any concept in biology could be mastered in two weeks,” Robinson says. “Much to everyone’s amazement, I not only passed my qualifying exam, but did much better than expected.”

It was at the University of California at Berkeley during her postdoctoral work that she met her husband. Although the marriage would not last the test of time, Robinson and her husband were blessed with three boys, each 13 months apart.

Robinson knew that she wanted to take time away from her career to stay home with her children before they entered primary school. As a graduate student at MIT, to prepare for both having a career and pursuing motherhood, Robinson hired a housekeeper and committed to being in the lab for only a typical 9 a.m. to 5 p.m. workday. If she were to compete with her male counterparts and be with her children, she needed to be able to get things done while working short hours. 

Robinson successfully completed her thesis work in just over two years.

“The difference between bearing children and rising up professional ladders is that you can start up the professional ladder after you are 40,” she advises. “Such is more problematic for having children.”

Robinson’s thesis work at MIT concerned how DNA, which is identical in all cells of an organism, produces different cell types from the same genetic blueprint. She explored this question through the lens of messenger RNA, a gene product that determines which DNA sequences are expressed in a cell. Later, her work on cancer-causing viruses in chickens would help lay the groundwork for gaining insight into genes that can cause tumors to form. 

“In contrast to becoming a wife, becoming a PhD from MIT did not falter, but rather provided me with the foundations for a career I loved in which I used molecular biology and chickens to study the genetic basis of cancer and pioneered the use of DNA as a new method of vaccination,” Robinson says.

Cancer-causing viruses

Robinson, supported by an National Science Foundation fellowship, pursued postdoc training at the University of California at Berkeley, in the lab of Harry Rubin. The Rubin Lab specialized in work on a virus known to cause cancer: the Rous sarcoma virus, which causes rapid tumor onset when introduced into chickens. RNA, it had recently been discovered, was the underlying genetic cause of tumors developing in chickens exposed to the Rous sarcoma virus. It cannot, however, do this deadly work without co-infection with something called a helper virus — in this case, avian leukosis virus. 

Both Rous sarcoma virus and its helper viruses were retroviruses, which can make DNA copies from RNA sequences, a departure from the previously accepted dogma that DNA is only transcribed into RNA, and not the other way around.

Robinson joined the Worcester Foundation for Biomedical Research in 1977, where she continued research on Rous helper viruses and had the opportunity to run her own lab for the first time. In 1998, she was recruited to be a professor of pathology at the University of Massachusetts Medical Center. While there, she conducted pioneering studies on the use of DNA for vaccination and worked on developing an AIDS vaccine. 

In 1999, she moved again, this time to step into the role of chief of microbiology and immunology at the Yerkes National Primate Research Center at Emory University, where she began testing her candidate HIV vaccines in primates. While at the University of Massachusetts and Emory, Robinson and her lab used DNA vaccines, both with and without a poxvirus booster vaccine provided by Bernie Moss at the National Institutes of Health, to immunize animals against influenza, HIV, measles, and Ebola.

“From the early days of DNA vaccines, I had wanted to start a company to help move DNA vaccines from bench to bedside,” she says. 

Thus, GeoVax, short for “Georgia Vaccines,” was born. Robinson co-founded it with Don Hildebrand in 2001 after her move to Yerkes; Robinson would serve as chief scientific officer and a member of the board of directors during her tenure at the company. 

GeoVax successfully moved Robinson’s candidate AIDS vaccine into human clinical trials. These trials were stopped due to the generally poor performance of HIV vaccines in clinical trials, compared to the outstanding therapeutic potential of more recently developed anti-HIV drugs. GeoVax, however, continues to work on vaccines for Mpox, Covid-19, and Ebola, and has expanded its scope to include a cancer treatment.  

A well-deserved retirement 

After rounds of good-natured roasting from colleagues at Emory University and GeoVax, Robinson retired and has been enjoying returning to Palo Alto, California, where her oldest son, Bill, and his wife now live. 

Ultimately, Robinson hopes that her story can encourage everyone, especially young women, not to let pursuing a challenging and enriching career prevent them from realizing the dream of having a family.

“I have had a wonderful life, far exceeding what I ever could have anticipated,” Robinson says. “I have had international adventure, the romance of a man who truly loved me, the joy of motherhood, and the warmth, wonder, and adventure of family and friends, and last, but not least, the exhilaration of a career in molecular biology.”

There are few treatment options available for people with disorders of the esophagus. Delivering drugs directly to this part of the body is difficult, so patients are usually treated with systemic drugs, which can have unwanted side effects.

To overcome that challenge, MIT engineers developed a gel-like oral drug formulation that can coat the mucosal lining of the esophagus after being swallowed, allowing drugs to pass through the tissue.

The formulation, which includes a hydrogel and other key ingredients that promote rapid drug absorption, could be used to deliver antibodies including infliximab, used to treat a number of autoimmune diseases, or other types of antibodies or small-molecule drugs.

“There are many people with esophageal disease, and if you look at drugs for these conditions, they’re very limited in their ability to target this part of the body and it’s very difficult to develop them. We hope this platform will make it easier to develop systems that can help patients suffering from these conditions,” says Giovanni Traverso, an associate professor of mechanical engineering at MIT, a gastroenterologist at Brigham and Women’s Hospital, and an associate member of the Broad Institute of MIT and Harvard.

Traverso is the senior author of the new study, which appears today in Nature Biomedical Engineering. Former MIT postdoc Christina Karavasili, now an assistant professor at Aristotle University of Thessaloniki in Greece, is the paper’s lead author.

Direct delivery

One of the most common disorders of the esophagus is eosinophilic esophagitis, a type of inflammation that is caused by food allergies and leads the esophagus to close up, making it impossible to swallow food. Crohn’s disease can also cause inflammation of the esophagus. 

These disorders are usually treated with systemic drugs, including infliximab, an antibody that neutralizes an inflammatory protein called tumor necrosis factor alpha (TNF-alpha). However, this drug is an immunosuppressant that can lead to a higher risk for infections and other health problems.

Delivering the drug directly to the esophageal tissue could reduce those side effects, but this is inherently challenging because drugs taken orally pass through the esophagus so quickly. Adding to the difficulty, the esophagus is lined by a layer of tissue called stratified squamous epithelium, which is very impermeable to drugs.

Injecting drugs into the esophageal tissue is another option, but that is uncomfortable for patients and inconvenient because it has to be done at a doctor’s office. There is also at least one anti-inflammatory steroid drug that is formulated as a thick mixture, allowing it to remain in the esophagus longer after being swallowed, but the drug still has some difficulty passing through the impermeable squamous layer.

In this study, the researchers set out to develop new drug formulations that would include molecules that could increase the permeability of those esophageal cells, allowing more of the drug to pass through. 

To identify molecules that would enhance permeability, the researchers designed a screening system that mimics the structure of the esophagus. This system contains esophageal tissue pressed between two vertical plates. Drug formulations can be poured into the top of the system, simulating oral ingestion. The researchers can then measure how much of the drug passes through the tissue and is collected by wells in one of the plates.

Using this system, the researchers were able to measure how different excipients — inactive ingredients that help enhance drug effects — affect the permeability of the esophageal tissue. First, they tested about 100 different compounds and identified several top candidates. Then, they tested pairs of these excipients and found that the most effective combination was a pair of bile salts called sodium chenodeoxycholate and sodium cholate.

These salts appear to work together to loosen up the cell-cell junctions that normally act as a barrier to drug molecule entry. The researchers added those bile salts to a polysaccharide-derived hydrogel, which has a viscous consistency that allows it to lightly coat the lining of the esophagus.

“The hydrogel helps the formulation remain on the esophageal surface for longer, while the bile salts help increase transport across the tissue,” Karavasili says. “Our data suggest that the bile salts temporarily loosen these cell–cell junctions, mainly by interacting with calcium ions that help maintain junction integrity. This creates a more permissive pathway between the cells, allowing larger molecules to move into the mucosal tissue more efficiently.”

Minimizing side effects

In tests in animals, the researchers showed that this formulation could be used to effectively deliver infliximab to the esophagus. They also found that the loosening of the cell-cell junctions was temporary, and the cells returned to normal within three days.

This kind of delivery could help to avoid the side effects that patients sometimes experience when infliximab is given systemically, the researchers say. 

“We were interested in delivering anti-TNFs as a model drug, but also to help people who suffer from conditions like Crohn’s disease to have options that could be delivered to the site,” Traverso says. “If we have the possibility of site-directed delivery, we may be able to mitigate systemic side effects from these immunosuppressing agents.”

The researchers are now working on further optimizing the formulation for potential testing in humans. One key goal is to ensure that the gel adheres for long enough to deliver the drugs, but not so long as to cause discomfort for patients. The researchers are also exploring the possibility of using this approach to deliver other types of drugs. 

“This is a platform to enable the development of drug-delivery systems for the esophagus, which hasn’t been possible before because the tools haven’t existed,” Traverso says.

The research was funded by the Karl van Tassel Career Development Professorship, the Department of Mechanical Engineering at MIT, the Division of Gastroenterology at Brigham and Women’s Hospital, and the U.S. Advanced Research Projects Agency for Health (ARPA-H), which notes that the views and conclusions contained in this article are those of the authors and should not be interpreted as representing the official policies of the United States government.

Debates about vaccines are a recurring feature of contemporary politics. It turns out they actually date back more than 200 years, since the development of the first smallpox vaccine. MIT Professor Thomas Levenson, one of the country’s leading science writers, explores this important history in a new book about the contours of anti-vaccination thought. Levenson identifies different types of arguments vaccination opponents have developed through history, to help shed light on our current debates. He spoke with MIT News about his new book, “A Pox on Fools: The True Believers, Grifters, and Cynics Who Convinced Us to Reject Vaccines,” published this week by Penguin Random House. 

Q: Your book is about the longer history of anti-vaccination arguments. How far back does this go, and what have those arguments been? 

A: Hesitation, skepticism, and outright opposition to vaccines is not a new thing. It didn’t just happen starting in the late 1990s. Opposition to vaccines dates back to the beginning of the vaccine era, around the early 19th century. The first kind of opposition to vaccines is this sense that it violates the moral or the natural order. If you believed that God has authority over all of us and is mindful of everything, intervening in the disease process could seem blasphemous. 

In the early 19th century, the first true vaccine, the smallpox vaccine, used material from a related disease, cowpox, that doesn’t cause human beings to fall ill but does provide immunity to smallpox. That shifted the initial focus on God’s plans to the notion that vaccination — sticking some cow-stuff into people — violated the natural order. That sort of uneasiness is easily co-opted by a broader philosophy that says: If you align yourself with nature, you don’t need to use vaccines. 

I want to emphasize that in the early history of the anti-vaccine movement, there were reasonable fears being expressed. That changes over time, because science advances and the mystery of vaccines falls away. Still, the current anti-vaccine movement includes an impulse we all have: We wish to be in control. I would never deny the value of exercise, sunlight, and sanitation, but they are not sufficient when you are faced with many pathogens, and that’s what the modern anti-vaccine movement obscures. We share this world with bacteria and viruses that do their thing no matter what we eat or how much we exercise. 

Q: One section of your book explores the argument that vaccines have been actively harmful. What is that historical trajectory like? 

A: The idea that vaccines are not just unnecessary but actively bad for you is certainly very contemporary, but it too goes back to the beginning of the vaccine era. The first true smallpox vaccine came into public use in 1798. Very soon afterward people started pointing to different harms. Most of them were spurious. They were just making things up or mistaking another infection that was already there. But there were some flaws in the early forms of vaccination. People thought it conferred life-long immunity, and that wasn’t always the case. Additionally, people mistook syphilis infections for cowpox infections and transmitted syphilis to healthy people. There were maybe 750 cases in Europe.

What is repeated over and over in the history of vaccination is that when problems became apparent, people found a way to address them. A problem with diphtheria antitoxin at the turn of the century led directly to the first U.S. regulatory body, the Division of Biological Controls. And when the first polio vaccine was released to the public in 1955, one of the five drug companies making it had shoddy production practices. Thousands got sick, a hundred died, and some were paralyzed. The flawed vaccine was identified after two weeks on sale and stopped cold, and that ended that particular problem. What came out of it was the development of an FDA vaccine division with teeth. 

This is an area where the rhetorical skill of the anti-vaccine movement is on display. Anything human beings do carries some risk. Anything you do medically. I had my hip replaced last year. That carries some risk, such as surgical site infections. Well, the risks of vaccines are incredibly small. The most common response is a sore arm the next day, and maybe feeling under the weather. There is extremely close control over manufacturing now. We have stories of great harm, but the various specific allegations of the last 30 or 35 years have proven to be incorrect. But there’s a power to an anecdote versus statistics. 

Q: This book raises an issue also explored in your last one, “So Very Small,” that the sheer success of vaccines has, paradoxically, created a situation in which people take their effects for granted and find it easier to argue against them. Can you explain this phenomenon?

A: The reason that occurs is because vaccines have worked so brilliantly well. At the turn of the century, life expectancy was much lower, 47 years in the U.S. Several top causes of death were infectious diseases, and child mortality was high. Now, life expectancy is around 80 years in every developed nation, and child mortality is a tiny fraction of 1 percent. By 1970, you had almost a complete set of vaccines against what used to be called childhood diseases. And those diseases, up until extremely recently, had essentially disappeared. And that’s amazing. 

In the 1950s, before the measles vaccine, for instance, everybody had an experience of what it meant to be at at the mercy of waves of infection. But by the 1970s, that was no longer the expected, ordinary, common experience of raising kids. So we’ve forgotten how unpleasant even an ordinary case of one of these diseases is that you recover from, much less the more severe problems and death. In 1952, there was the largest polio outbreak in U.S. history, and it was scary to let your kid go to the movies or a swimming pool. They could go to someone’s birthday party, come back, and two weeks later start feeling muscle aches and a fever, and two weeks after that were maybe paralyzed, or dead. Then in 1955 the Salk polio vaccine came out. We don’t live that way any more. 

And so, because infectious disease seems like a nonexistent threat, vaccines, even with a tiny potential of harm, are made to seem worse because we don’t realize what happens if we let our vaccine coverage lapse. Well, we’re starting to get a glimpse of it, because the measles rate in the U.S. is shooting up, and we see what happens when vaccine coverage wanes, and in particular, when we lose herd immunity. In every population, some people cannot be vaccinated: infants who are too young, some people who have had transplants and are on immunosuppressive drugs, or the elderly in whom sometimes immunity wanes. Some diseases are so infectious, and measles is famous for this, that about 95 percent of a population must be vaccinated or the disease spreads. If we’re not at that threshold, every newborn is at risk. 

We don’t know what it’s like to live with the genuine risk and fear of those diseases. If you were born in 1970, you’re 56 now, and you literally never lived in a world where these diseases were common. 

Q: One source of resistance to vaccines is not strictly medical, but political and philosophical at one level. This also has a lengthy history, it seems. 

A: Another major theme of the anti-vaccination movement is to argue the question: Who has the right to say that somebody else must put something in their body? Again, all this is not new: In the mid-19th century, in the United Kingdom, there was a requirement that children be vaccinated against smallpox, and these mandates brought immediate opposition as an infringement of liberty. 

In 1850 the country’s top doctor, John Simon, physician to the privy council in England, described the right that people claim against vaccination as the liberty of “omissional infanticide,” that you are killing kids by not protecting them. Where do I stand? This is a philosophical question. Does the state have the right to make me do something because it will make society as a whole safer? I think, “Yes.” We live in societies, we depend on each other for all kinds of things, we aren’t just atomized individuals. But I can understand those who say, “No.” I just think it’s wrong. But it’s an argument that’s winning in some places. What I realized as I worked on this book is that the argument against vaccination on philosophical grounds is a lonely view: I owe nothing to anyone, and nothing owes anything to me. I think it’s a fearful one, too.

Q: For the vaccine hesitant, for those questioning vaccines, what will they get out of this book? 

A: On social media you see some people calling vaccine-hesitant people stupid, but that’s not right. People are busy. We all have daily lives. Get the kids ready for school, pack their lunches, go to work, get home, fix dinner. All of us offload some decisions to people we trust as experts. I have a ton of sympathy and empathy both for people trying to think how to make it through an incredibly complicated world. They hear noise about how vaccines are problematic and there’s no easy way for them to get to the bottom of the issue. That’s an opening the anti-vaccine movement exploits.

I hope my book reaches people who are vaccine hesitant. It’s understandable that people might think that where there’s smoke, there’s fire. But when you get down to the bottom question: Do vaccines help human flourishing, do they support the ability of human beings to live healthy, fulfilled lives? Yes, they do. Unequivocally, they are the greatest lifesaving invention humankind has ever come up with.

Jinhua Zhao MCP ’04, SM ’04, PhD ’09 has been appointed head of the Department of Urban Studies and Planning (DUSP), effective July 1. Zhao is the Class of 1941 Professor of Cities and Transportation at MIT.

In making the announcement, dean of the MIT School of Architecture and Planning Hashim Sarkis noted that Zhao is a renowned transportation planner, educator, and scholar, and a world leader in imagining and shaping better futures for mobility.

“Jinhua is one of those rare scholars who moves seamlessly between cutting-edge research and real-world policy,” says Sarkis. “His work with governments and transportation agencies around the world is a model for what MIT’s impact can look like beyond our campus.” 

Zhao succeeds Professor Christopher Zegras, who has served as department head since 2020. Under his leadership, DUSP expanded opportunities for students to engage directly with communities and policymakers around the world and continued to strengthen its long-standing connection between research and practice. “I want to extend my gratitude to Chris Zegras for his excellent and level-headed leadership, especially in challenging times,” says Sarkis.

After earning advanced degrees at MIT, Zhao joined the DUSP faculty. He says he found the Institute’s lack of conventionality and its culture of sharing ideas across disciplines stimulating. 

“MIT is a small school in the best sense of the word,” says Zhao. “We have fewer boundaries than other universities — intellectually and physically. Our ‘infinite corridor’ literally connects us to so many disciplines.”  

Shaping mobility systems worldwide 

That connectivity has been key for Zhao’s research and programs he has founded at MIT. Respected as a global authority on mobility, his research has been put into practice across some of the world's most complex mobility challenges. He and his team have shaped policy for Transport for London, the Mass Transit Railway in Hong Kong, and Japan Railways. His research has positively impacted leading U.S. transit authorities including Boston’s MBTA, the Chicago Transit Authority, and Washington’s Metropolitan Area Transit Authority. He has guided strategic planning for mobility industry on the future of autonomous and digital mobility, and developed autonomous vehicle (AV) deployment strategy in Singapore and the Middle East.

“Every city I’ve worked with faces the same tension: The technology is moving faster than the institutions designed to govern it,” says Zhao. “My work has been about closing that gap.”

At MIT, Zhao founded the MIT Mobility Initiative, which engages mobility and transportation researchers across the Institute as well as leaders in these disciplines from around the world. Zhao hosts the weekly MIT Mobility Forum via Zoom, with each discussion open to the public. What began as a small internal list of participants has grown into a global platform, drawing more than 200 practitioners, policymakers, and researchers every week around the world. The sizeable interest in the subject doesn’t surprise Zhao.

“No single discipline owns transportation,” says Zhao. “AI and autonomous systems are reshaping urban living faster than most institutions can adapt. The question is no longer what we know. It is whether the people who need it most — municipal governments, transport agencies, federal ministries — can access it when they make decisions on transportation. This is why the forum exists.”

Zhao directs the JTL Urban Mobility Lab that unites behavioral science and transportation technology to shape travel behavior, design mobility systems, and improve transportation policies. He is also a lead principal investigator with Mens, Manus, and Machina, an MIT initiative at the intersection of artificial intelligence, the future of work, and human learning, developing the tools and strategies for how cities, institutions, and economies can be designed to ensure AI augments, rather than displaces, the people within them.

DUSP’s global agenda

“If you look at the global agenda, what are the issues people are facing?” asks Zhao. “An aging society; AI and its impact on jobs; the energy crisis; traffic congestion. These are just some of the problems people feel connected to because they are embodied in our cities and communities. I want DUSP to engage with the city leaders and share our research and insights.” 

As he prepares to step into his role as department head, Zhao says he would like the research generated within DUSP to more quickly reach those who need it most: the planners, officials, and engineers making decisions in cities right now. A transit authority grappling with AV integration; a city government rethinking aging infrastructure; a leading transport ministry navigating the policy implications of AI — these are the constituencies Zhao believes DUSP should be in active conversation with.

“We know a great deal about how cities grow, how people move, and how that will change. The question is whether the people responsible for making these changes — in city halls, transport agencies, federal ministries — can access what we know, when they need it.”

Last fall, MIT Campus Dining recruited a group of students to make short videos and share their experiences as student diners on Instagram. The MIT Dining Ambassadors program is an effort to get students talking about — and helping to improve — MIT’s food services and systems. 

One of the inaugural ambassadors, Michaela Brown, a biochemical engineering major from Kingston, Jamaica, sat down to discuss what she’s learning as an ambassador, how she has adapted to dining-hall life, the best things about her mom’s cooking, what it was like to experience American Thanksgiving for the first time, and more.

Q: How did you get involved in the Dining Ambassadors program? 

A: Last October, my friend got a job. So I was like, I need to get a job. When I read the description, I said, Wait, this involves food, and talking to people, and posting on Instagram? That’s literally what I do every day. And I wanted to do my part. 

The ambassadors program has clear goals: They want to encourage students to use the dining halls, and they want us to find genuine issues MIT can work on. I wanted to be a part of that. The food at MIT is OK, but everything can be better. And you can’t make things better in any circumstance without trying. Plus — getting paid to eat food and talk? That is good money.

Q: What did you eat growing up? 

A: I love Jamaican food. On Sunday, we do a big dinner. (Well, my mom would do a big dinner; sometimes I would wash the vegetables.) She would cook rice, peas, and vegetables with a sauce, and either fried chicken with sauce or stewed chicken. We would eat that food on Sunday, and then maybe Monday, too. We call it “Sunday-Monday” in Jamaica. 

During the week, we eat flour dumplings, boiled green bananas, and lots of plantains. Sometimes, when my mom is on a health kick, she will boil everything, but plantains are so much better when you fry them! Often, she will serve that with ackee. That’s our national food. And she will cook saltfish or mackerel mixed with coconut milk. She also makes things like corned beef or tuna. On Fridays, we usually go out. 

For special occasions, sometimes we do pork or oxtail. Or sometimes we have escovitch fish; I think you fry it and you steam it. And then we have sides like dumpling, or banana, or bami, which is fried flour. And usually we eat these with okra and pickled onions, and add a little spice with Scotch bonnet pepper. 

And curry chicken! If I am home and I smell the curry, I get so happy. I genuinely feel better about myself. If you’re buying food from a vendor, like fried chicken and rice, you would ask for curry gravy because it is very essential in Jamaican culture. 

Q: What was your first project for the ambassadors program?

A: I did a video about Thanksgiving. I was excited, because it would be my first American Thanksgiving. As a kid in Jamaica, I saw it on TV. I watched Nickelodeon. Also, we learned about it in school. But we didn’t do Thanksgiving in Jamaica. So I was excited.

In the video, I was trying to cater to students who don’t normally celebrate Thanksgiving and show them the experience from a fresh perspective. I brought my friends with me and we all ate together. And luckily everyone thought the food was good. I really wanted to show the food — the mashed potatoes, the turkey, the jelly, the ham, all those things — because I think New Vassar did it really well. I wanted to show that. 

There are a lot of international students at MIT. I didn’t know what MIT was like until I got here. I wanted to show that I came here and liked it. Even while I was missing home, I was being introduced to other cultures — like the one in America — and MIT was helping me appreciate it through food.

Also, I wanted to show the community — being with my friends, giving thanks for the people around me. I really enjoyed that, and I thought it went well. My mom loved it.

Q: What have you done since then? 

A: Usually, I just try to take pictures when I’m in a dining hall and post them on Instagram. You know — regular life.

The other major thing was the global Olympics. Each day over two weeks, they had a special theme at each of the dining halls — Latin American at New Vassar, East Asian at Simmons, African at McCormick, European at Next House, Indian at Massey, and North American and Caribbean at Baker. 

My favorite was Baker, because, well, I’m a little biased. And also, I love the burgers at Baker. 
I told my friends they had to come. A lot of the cooking staff in Baker are Haitian. They would know how food from Haiti and Jamaica should taste. I knew they wouldn’t mess it up. 

I interviewed a lot of students, including two Haitians and one of my Jamaican friends. I asked about the food, about how it compared to regular dining hall meals. They were really positive. I think they liked the change. 

Q: Do you like to cook? 

A: Not really. The summer before I came here, I was like, OK, I’m gonna learn something. 
And then I proceeded to spend the summer out with my friends, and volunteering. So I wasn’t really in the kitchen. My mom would call me to come help her, and when I stepped in the kitchen it was so hot! I was like, I can’t do this, and I went back to my room. 

So I’m not really a cook, even though I live in Burton-Connor. It’s a cook-for-yourself dorm, so it doesn’t have a dining hall. A few weeks ago, I tried to do burritos. I got the beef and the seasoning. It was actually really good! I’m looking forward to it again. It’s just really hard to find the time. 


Q: When you’re posting, who do you imagine is looking at it? 

A: My friends. And my mom. Honestly, I just try to make sure you can understand what I’m saying because sometimes my Jamaican patois comes out, and I talk too fast. I also think about how the people I’m interviewing want to be seen, because this is not their job. They don’t have to be on camera, or help me. I try to make the experience as fun as possible for them. 

Q: What have you learned doing this work?

A: Walking up to strangers and getting their permission to record them is really new to me. I have learned so much about people. The other day, I was looking at a job application and it asked: Are you comfortable talking to other people and being social? This job has prepared me for all that so well. 

It also prepared me for dealing with people who might not be open to talking. I have learned to be OK with that, just walking away and handling it well. This is a skill set that I have now, and I look forward to working more and doing more interviews. I feel like, you know, a YouTuber!

Q: What dining stories do you want to tell next? 

A: I’m not sure. Dining is different for different people. For me personally, sometimes eating is a time to get together with other people. But sometimes I go to the dining hall by myself. It’s very much a time for me to decompress. Sometimes I don’t even want anyone to sit with me. I’m just trying to be with myself, watch my show, or do the learning sequence I have due at 11 o’clock. Or I just watch my TikToks. 

Maybe I’ll do a day-in-my-life dining story next, and go for breakfast at a dining hall. I would have to wake up earlier, but I would do it.